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Background: Joint awareness reflects patient satisfaction and prosthesis integration after arthroplasty. This study aimed to evaluate joint awareness differences between robotic-assisted joint arthroplasty (R-JA) and manual joint arthroplasty (M-JA) across various joint sites and follow-up periods.
Methods: A systematic search was conducted in four major databases for studies published between January 1, 2012, and February 1, 2025. Cohort studies and randomized controlled trials comparing R-JA and M-JA were included. Studies reporting the Forgotten Joint Score (FJS-12) were selected, with data extracted and categorized by follow-up duration: short-term (< one year), mid-term (one to two years), and long-term (> two years). Descriptive statistics and a random-effects model were applied. A total of 39 studies were included, encompassing 13,289 joints, comprising 10,037 total knee arthroplasties (TKAs), 2,781 total hip arthroplasties (THAs), and 471 unicompartmental knee arthroplasties (UKAs).
Results: The meta-analysis indicated that R-TKA achieved higher FJS-12 than M-TKA across all follow-up periods (short-term: mean difference (MD): 5.72, 95% confidence intervals (CI): 1.37 to 10.07; mid-term: MD: 3.27, 95% CI: 0.11 to 6.42; long-term: MD: 8.37, 95%CI: 0.86 to 15.89). Similarly, R-THA consistently outperformed M-THA in joint awareness across all follow-up periods (within one year: MD: 6.60, 95% CI: 3.47 to 9.74; one to two years: MD: 7.19, 95% CI: 1.21 to 13.17; over two years: MD: 1.92, 95% CI: 0.46 to 3.39). The R-UKA demonstrated superior FJS-12 in short-term (MD: 7.88, 95% CI: 4.02 to 11.74) and mid-term (MD: 12.96, 95% CI: 7.27 to 18.66) follow-ups, but no significant difference was observed in the long-term follow-up (MD: 9.06, 95% CI: -7.76 to 25.89).
Conclusions: This study found that R-JA improved joint awareness after total joint arthroplasty, with a consistent advantage in TKA and THA across all follow-up periods, while the benefits in UKA were limited to within two years.
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http://dx.doi.org/10.1016/j.arth.2025.08.024 | DOI Listing |
J Appl Stat
January 2025
Department of Sociology, University of Pennsylvania, Philadelphia, PA, USA.
This paper presents a causal inference estimation method for longitudinal observational studies with multiple outcomes. The method uses marginal structural models with inverse probability treatment weights (MSM-IPTWs). In developing the proposed method, we re-define the weights as a product of inverse weights at each time point, accounting for time-varying confounders and treatment exposures and possible correlation between and within (serial) the multiple outcomes.
View Article and Find Full Text PDFBackground: Kikuchi-Fujimoto disease (KFD) is a benign, self-limited, rare disease that rarely coexists with hemophagocytic lymphohistiocytosis (HLH).
Methods: We reported a case of a young female who presented with recurrent fever accompanied by painful lymphadenopathy, joint pain, and skin rash.
Results: Excisional biopsy of lymph node indicated KFD.
Oman Med J
March 2025
Department of Family Medicine and Public Health, Sultan Qaboos University, Sultan Qaboos University Hospital, Oman.
Zoledronic acid is commonly used to treat osteoporosis and it is generally well tolerated. We describe the case of a woman with osteoporosis, who developed a flare-up of osteoarthritis hours after receiving a single dose of zoledronic acid. She developed fever with chills, generalized body aches, and severe low back pain.
View Article and Find Full Text PDFInt J Antimicrob Agents
September 2025
Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada; European Society of Clinical Microbiology and Infectious Diseases (ESCMID) Study Group for Non-Traditional Antibacterial Therapy (ESGNTA); Phage Canada, Maple, Ontario, Canada; Unity Health Toronto,
With antimicrobial resistance as a worldwide public health concern, bacteriophage (phage) therapy (PT) may help treat bacterial infections. However, given its particularities compared with traditional small molecule drugs, there are variations in how it is regulated worldwide. Regulators are key players governing PT, yet their perspectives have been largely unexplored.
View Article and Find Full Text PDFIEEE Trans Pattern Anal Mach Intell
September 2025
Generalized visual grounding tasks, including Generalized Referring Expression Comprehension (GREC) and Segmentation (GRES), extend the classical visual grounding paradigm by accommodating multi-target and non-target scenarios. Specifically, GREC focuses on accurately identifying all referential objects at the coarse bounding box level, while GRES aims for achieve fine-grained pixel-level perception. However, existing approaches typically treat these tasks independently, overlooking the benefits of jointly training GREC and GRES to ensure consistent multi-granularity predictions and streamline the overall process.
View Article and Find Full Text PDF