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Visual object tracking has witnessed continuous advances in recent years along with the exciting developments in backbone networks. In general, all advanced solutions adhere to the template-based tracking framework, which exhibits powerful representative capacity gained via offline training. However, when the target undergoes appearance changes or occlusion, the tracker, which relies on a fixed template defined in the initial frame, struggles to locate it accurately in such complex situations. To achieve online adaptation, recent studies have introduced dynamic templates. Typically, the adopted solution is to compute reliability scores in the traditional Euclidean space to assess the confidence of the dynamic template. However, the Euclidean metric is unreliable to some extent in high-dimensional feature spaces, potentially resulting in a negative impact by involving incorrect dynamic templates. To overcome this problem, we exploit the compact geometric representation capacity of the Symmetric Positive Definite (SPD) manifold to design a novel score prediction module for the tracker update (SPD-Updater). By switching to an SPD manifold metric, we obtain a more accurate and stable dynamic template, thereby enhancing the model capacity to handle complex situations. To validate the reliability of manifold metric in tracking models, we conduct experiments with trackers using different backbones. The experimental results on LaSOT, GOT-10k, TrackingNet, and UAV123 demonstrate the effectiveness of our approach, reflecting the merit of the SPD metric in online tracking adaptation.
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http://dx.doi.org/10.1016/j.neunet.2025.107985 | DOI Listing |
Analyst
September 2025
Research Centre for Analytical Instrumentation, State Key Laboratory of Industrial Control Technology, Zhejiang University, Hangzhou 310027, P. R. China.
Rapid and efficient screening of foodborne pathogens is crucial for preventing bacterial spread and food poisoning. However, developing a multi-detection method that is easy to operate, offers good stability, and achieves high efficiency remains an enormous challenge. Existing multiplexed nucleic acid detection methods suffer from complex designs, leading to complicated operations, and non-robust sample introduction, causing primer/probe crosstalk and false-positive results.
View Article and Find Full Text PDFNeurology
October 2025
Norcliffe Foundation Center for Integrative Brain Research, Seattle Children's Research Institute, WA.
Background And Objectives: Neuroimaging findings in immune effector cell-associated neurotoxicity syndrome (ICANS) have not been systematically described. We created the chimeric antigen receptor (CAR) T-cell Neurotoxicity Imaging Virtual Archive Library (CARNIVAL), a centralized imaging database for children and young adults receiving CAR T-cell therapy. Objectives of this study were to (1) characterize neuroimaging findings associated with ICANS and (2) determine whether specific ICANS-related neuroimaging findings are associated with individual neurologic symptoms.
View Article and Find Full Text PDFNat Commun
September 2025
Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Faculty of Medicine, Lund University, Lund, Sweden.
The distribution of tau pathology in Alzheimer's disease (AD) shows remarkable inter-individual heterogeneity, including hemispheric asymmetry. However, the factors driving this asymmetry remain poorly understood. Here we explore whether tau asymmetry is linked to i) reduced inter-hemispheric brain connectivity (potentially restricting tau spread), or ii) asymmetry in amyloid-beta (Aβ) distribution (indicating greater hemisphere-specific vulnerability to AD pathology).
View Article and Find Full Text PDFCirc J
September 2025
Department of Cardiovascular Medicine, Shinshu University School of Medicine.
Background: With an increase in the aging population, heart failure (HF) has become a major healthcare problem. Therefore, early detection of key signals characteristic of each of the stages of HF has the potential to improve treatment and palliative care. Metabolomics profiling may be useful in identifying biomarkers of HF and improving HF treatment.
View Article and Find Full Text PDFChemSusChem
September 2025
i-Lab & CAS Key Laboratory of Nanophotonic Materials and Devices, Suzhou Institute of Nano-Tech and Nano-Bionics, Chinese Academy of Sciences, Suzhou, 215123, China.
Solid-state lithium metal batteries (SSLMBs) are promising for realizing higher energy density. However, the poor interfacial Li transport kinetics and Li dendrite growth inhibit SSLMBs, leading to sluggish interfacial ion diffusion and depressive lifespan, which is attributed to high barriers blocked by anions or interface space in solid-state electrolytes. Herein, a flexible solid-state polymer skeleton employed with ionic liquid and metal-organic frameworks (PIM) electrolyte is proposed to strengthen interfacial Li ion exchange by improving the Li sieving effect and interfacial wettability.
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