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Examination of the effectiveness of an attention intervention using a randomized controlled trial for toddlers with suspected or confirmed autism spectrum disorder (ASD). Data was collected from Alberta, Ontario, and Nova Scotia, Canada between February 2018 and February 2020 (halted due to COVID-19 pandemic). Participants were 35 toddlers randomized to the attention condition (age at start: 25.49 + 3.91 months; 29 boys; mother's ethnicity: 65% white) and 34 toddlers randomized to a control condition. (age at start: 26.32 + 3.55 months; 24 boys; mother's ethnicity: 29% white). The results suggest that the attentional skills can be improved by a computer-based attention intervention, which in turn affects behavior observed in a real-world setting.
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http://dx.doi.org/10.1111/cdev.70033 | DOI Listing |
Hum Brain Mapp
September 2025
Tri-Institutional Center for Translational Research in Neuroimaging and Data Science (TReNDS), Georgia State University, Georgia Institute of Technology, and Emory University, Atlanta, Georgia, USA.
Investigating neuroimaging data to identify brain-based markers of mental illnesses has gained significant attention. Nevertheless, these endeavors encounter challenges arising from a reliance on symptoms and self-report assessments in making an initial diagnosis. The absence of biological data to delineate nosological categories hinders the provision of additional neurobiological insights into these disorders.
View Article and Find Full Text PDFComput Methods Biomech Biomed Engin
September 2025
Institute of Radio Physics and Electronics, University of Calcutta, Kolkata, India.
Parkinson's disease (PD) is a neurodegenerative condition that impairs motor functions. Accurate and early diagnosis is essential for enhancing well-being and ensuring effective treatment. This study proposes a deep learning-based approach for PD detection using EEG signals.
View Article and Find Full Text PDFInt J Plant Anim Environ Sci
August 2025
Department of Translational Research, College of Osteopathic Medicine of the Pacific, Western University of Health Sciences, Pomona, CA 91766, USA.
Neurological disorders, such as Alzheimer's disease, Parkinson's disease, epilepsy, spinal cord injuries, and traumatic brain injuries, represent substantial global health challenges due to their chronic and often progressive nature. While allopathic medicine offers a range of pharmacological interventions aimed at managing symptoms and mitigating disease progression, it is accompanied by limitations, including adverse side effects, the development of drug resistance, and incomplete efficacy. In parallel, phytochemicals-bioactive compounds derived from plants-are receiving increased attention for their potential neuroprotective, antioxidant, and anti-inflammatory properties.
View Article and Find Full Text PDFNat Sci Sleep
September 2025
Department of Geriatrics, Tianjin Medical University General Hospital; Tianjin Key Laboratory of Elderly Health; Tianjin Geriatrics Institute, Tianjin, People's Republic of China.
Background: Sleep and frailty are established influencing factors for cardiometabolic diseases (CMDs). However, their joint effects on cardiometabolic multimorbidity (CMM) in older adults remain poorly understood. This study aimed to assess the joint effect of sleep health and frailty on CMD prevalence and severity, with an emphasis on subgroup-specific health risk profiles.
View Article and Find Full Text PDFFront Bioeng Biotechnol
August 2025
Department of Orthopaedic and Reconstructive Surgery/Pediatric Orthopaedics, South China Hospital, Medical School, Shenzhen University, Shenzhen, China.
Distraction osteogenesis (DO) is an endogenous bone tissue engineering technique that harnesses the regenerative potential of bone and has been widely applied in limb lengthening, bone defect repair, and craniofacial reconstruction. The DO procedure consists of three distinct phases: the latency phase, the distraction phase, and the consolidation phase, each characterized by unique biological processes. In recent years, increasing attention has been directed toward the role of the immune system during DO.
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