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The nursery and finishing phases are critical for profitability and sustainability in swine production, but effective methods for early disease detection in these stages remain underdeveloped. This study used routinely collected production indicators from nursery (42-56 days postfarrowing) and finishing lots (115-120 days postfarrowing) to create production benchmark curves for anomaly detection. These curves were developed for farms without diagnosed health challenges and compared to those with diagnosed health issues, based on tissue submissions and diagnostic codes (Dx codes). Statistical methods such as resampling techniques, Bayesian statistics, and standard deviation (SD) thresholds were employed to build the benchmark curves. The main objective was to test and compare the benchmarks using detection, early detection rate (EDR), time-to-detect (TTD), and false positive rate (FPR). Results showed that bootstrapping (BOOT), jackknife (JK), and Markov chain Monte Carlo (MCMC) methods provided the highest EDRs, although they were prone to false positives. For nursery lots, it was observed that using cumulative average with one SD for feed disappearance (EDR 49.2% and FPR 9.8%) and estimated weight (EDR 47.2% and FPR 8.8%) showed the best balance between EDR and FPR, and using MCMC for mortality showed the best balance between EDR and FPR (EDR 38.8% and FPR 13.8%). For finishing lots, using cumulative average with one SD showed a more balanced performance with FPR below 14.0% and EDR of 21.3% for feed disappearance, 67.4% weight, and 59.7% for mortality. These findings demonstrate the potential of using production indicators for early health challenge detection in swine operations.
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http://dx.doi.org/10.1155/tbed/9952020 | DOI Listing |
J Appl Clin Med Phys
September 2025
Department of Radiation Oncology, University of Utah, Salt Lake City, Utah, USA.
Purpose: The development of on-board cone-beam computed tomography (CBCT) has led to improved target localization and evaluation of patient anatomical change throughout the course of radiation therapy. HyperSight, a newly developed on-board CBCT platform by Varian, has been shown to improve image quality and HU fidelity relative to conventional CBCT. The purpose of this study is to benchmark the dose calculation accuracy of Varian's HyperSight cone-beam computed tomography (CBCT) on the Halcyon platform relative to fan-beam CT-based dose calculations and to perform end-to-end testing of HyperSight CBCT-only based treatment planning.
View Article and Find Full Text PDFJ Robot Surg
September 2025
Department of General Surgery, Giglio Hospital Foundation, Cefalu', Italy.
The adoption of robotic pancreatectomy has grown significantly in recent years, driven by its potential advantages in precision, minimally invasive access, and improved patient recovery. However, mastering these complex procedures requires overcoming a substantial learning curve, and the role of structured mentoring in facilitating this transition remains underexplored. This systematic review and meta-analysis aimed to comprehensively evaluate the number of cases required to achieve surgical proficiency, assess the impact of mentoring on skill acquisition, and analyze how outcomes evolve throughout the learning process.
View Article and Find Full Text PDFJ Vis Exp
August 2025
Department of Computer Science and Engineering, Gokaraju Rangaraju Institute of Engineering and Technology, Hyderabad, India.
Deepfakes pose critical threats to digital media integrity and societal trust. This paper presents a hybrid deepfake detection framework combining Convolutional Neural Networks (CNNs) and Generative Adversarial Networks (GANs) to address challenges in scalability, generalizability, and adversarial robustness. The framework integrates adversarial training, a temporal decay analysis model, and multimodal detection across audio, video, and text domains.
View Article and Find Full Text PDFAn integrated approach is proposed to rapidly evaluate the effects of anticancer treatments in 3D models, combining a droplet-based microfluidic platform for spheroid formation and single-spheroid chemotherapy application, label-free morphological analysis, and machine learning to assess treatment response. Morphological features of spheroids, such as size and color intensity, are extracted and selected using the multivariate information-based inductive causation algorithm, and used to train a neural network for spheroid classification into viability classes, derived from metabolic assays performed within the same platform as a benchmark. The model is tested on Ewing sarcoma cell lines and patient-derived xenograft (PDX) cells, demonstrating robust performance across datasets.
View Article and Find Full Text PDFSci Rep
September 2025
Institute of Diagnostic and Interventional Radiology and Neuroradiology, University Hospital Essen, Hufelandstraße 55, 45147, Essen, Germany.
In radiomics, feature selection methods are primarily used to eliminate redundant features and identify relevant ones. Feature projection methods, such as principal component analysis (PCA), are often avoided due to concerns that recombining features may compromise interpretability. However, since most radiomic features lack inherent semantic meaning, prioritizing interpretability over predictive performance may not be justified.
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