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Objectives: Blood Disease of Banana brought on by Ralstonia syzygii subsp. celebesensis (Rsc) results in yield losses in Indonesia up to 90%. Among the symptoms are wilting, vascular staining, fruit rot, and plant death. Pathogen travels via contaminated tools, water runoff, pests, and pollinators. Originally reported in South Sulawesi, it now affects all of the main Indonesian islands as well as Malaysia. Though its influence is known, understanding of Rsc pathogenesis is less than that of Ralstonia solanacearum. This study investigates the different genome of Rsc isolate from Bali, geographically separated by the Wallace Line, and compares them to published genomes from Yogyakarta.
Data Description: The data presented were obtained as a byproduct of a broader genomic survey on Rsc diversity. The genome structure and G + C content analysis of Rsc, which was isolated from Musa balbisiana cultivar Kepok in Bali, is included in the draft genome sequence. The genome's size, coding sequence patterns, and functional annotations were assessed after being assembled from scratch. Genome analysis pipeline was used to process each sequencing data separately using protocols created for Oxford Nanopore sequencing outputs. Comparative analysis with the Yogyakarta isolate highlights molecular variations likely influenced by geographic isolation across the Wallace Line.
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http://dx.doi.org/10.1186/s13104-025-07398-7 | DOI Listing |
Hum Genome Var
September 2025
Department of Molecular Endocrinology, National Research Institute for Child Health and Development, Tokyo, Japan.
Here, using whole-exome sequencing of a cohort of 17 Japanese patients with 46,XY disorders or differences of sex development, we identified two pathogenic DEAH-box helicase 37 (DHX37) variants in three patients. We also identified a patient with a likely pathogenic variant in SOX9 and a rare likely benign variant in DHX37. This Data Report highlights the genetic and phenotypic diversity of DXH37 variants.
View Article and Find Full Text PDFJ Cosmet Dermatol
September 2025
School of Light Industry Science and Engineering, Beijing Technology and Business University, Beijing, People's Republic of China.
Background: In recent years, the problem of female alopecia has been increasing and has shown a trend toward youthfulness. However, there are fewer studies on young female alopecia in the existing literature.
Aim: We aimed to study the possible causes of hair loss in young Chinese females aged 18-35 with oily scalps.
Pestic Biochem Physiol
November 2025
State Key Laboratory of Agricultural and Forestry Biosecurity, College of Plant Protection, Nanjing Agricultural University, Nanjing 211800, PR China. Electronic address:
The insect ionotropic γ-aminobutyric acid (GABA) receptor is an important insecticide target, and alternative splicing (AS) among exons 3a, 3b, 6a, and 6b of its RDL subunit is ubiquitous in insects; however, the AS factors and mechanisms remain unclear. While the neuro-oncological ventral antigen (Nova) is known to regulate AS of the γ2 subunit of mammalian GABA receptors, its role in insects remains unexplored. Two CsNova isoforms, CsNova-X1 and CsNova-X3, were identified by BLAST in the third-generation transcriptome of Chilo suppressalis.
View Article and Find Full Text PDFPestic Biochem Physiol
November 2025
School of Life Sciences, Chongqing University, Chongqing 401331, China; Chongqing Engineering Research Center for Fungal Insecticides, Chongqing 401331, China; Key Laboratory of Gene Function and Regulation Technologies under Chongqing Municipal Education Commission, Chongqing 401331, China; Nationa
Entomopathogenic fungi such as Metarhizium acridum are pivotal for sustainable pest management, yet the industrial conidial production is hindered by low yields and environmental sensitivity. Transcriptional regulation provides key targets for engineering strain modification. AP-1 transcription factors (TFs) are well-known for their roles in fungal growth, development, conidiation, pathogenicity and stress tolerance across various fungi.
View Article and Find Full Text PDFPestic Biochem Physiol
November 2025
Key Laboratory of Zoological Systematics and Application of Hebei Province, College of Life Sciences, Hebei University, Baoding, China. Electronic address:
The 20S proteasome is a core component of the ubiquitin-proteasome system, participating in various biological processes such as cell cycle regulation, signal transduction, apoptosis, and protein homeostasis. However, its roles in mammals are well-documented, its function in the insect intestine remains largely unexplored. In this study, we identified 14 20S proteasome subunits, including 7 α-subunits and 7 β-subunits in Locusta migratoria, a worldwide agricultural pest.
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