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Article Abstract
We hypothesize that stress-induced RNA structural changes, stabilized by RNA-binding proteins in biomolecular condensates, propagate via conformational catalysis in a prion-like manner across generations. Our model suggests that RNA structure encodes heritable memory, and its roles should be explored in epigenetic inheritance, evolutionary adaptation and disease.
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| http://dx.doi.org/10.1038/s41556-025-01736-4 | DOI Listing |
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