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Article Abstract
Purpose: To investigate the relationship between visual function, optical coherence tomography (OCT) parameters, and optic nerve bending before and after tumor resection in adult patients with craniopharyngioma.
Study Design: Retrospective observational study.
Methods: We retrospectively evaluated 22 eyes of 11 adult patients with craniopharyngioma who underwent tumor resection surgery. We assessed the preoperative and 1-month postoperative best-corrected visual acuity (BCVA), simple visual field impairment score (SVFIS) for visual field evaluation, 6-segmented macular ganglion cell layer (GCL) + inner plexiform layer (IPL) and 4-segmented circumpapillary retinal nerve fiber layer (cpRNFL) thickness, and optic nerve-canal bending angle (ONCBA).
Results: Bilateral hemianopia was observed in 10 patients (91%), whilst homonymous hemianopia was observed in 1 patient (9%). The BCVA and SVFIS scores improved significantly postoperatively (both P <.001), and eyes with optic nerve bending had significantly worse preoperative BCVA and SVFIS (both P <.001), and the ONCBA was significantly correlated with preoperative BCVA, SVFIS, and GCL+IPL thickness in all areas. OCT detected superior nasal GCL+IPL thinning in 10 eyes (45%) and superior cpRNFL thinning in 2 eyes (9%).
Conclusion: In adult patients with craniopharyngioma, GCL+IPL and cpRNFL thicknesses were associated with postoperative visual function recovery. The ONCBA was associated with preoperative visual dysfunction. ONCBA, GCL+IPL, and RNFL thicknesses may be useful for monitoring visual function in adult craniopharyngiomas preoperatively and postoperatively.
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| http://dx.doi.org/10.1007/s10384-025-01267-3 | DOI Listing |
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