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Transcatheter aortic valve replacement (TAVR) has become a transformative therapy for patients with severe aortic stenosis, offering a minimally invasive alternative to surgical valve replacement across all risk categories. Although outcomes are generally favorable, rare but potentially life-threatening complications such as prosthetic valve embolization and aortic dissection can pose significant challenges, even for experienced multidisciplinary cardiovascular teams. We report the case of an 87-year-old man with severe aortic stenosis and multiple comorbidities who underwent elective transfemoral TAVR using a 26-mm Edwards SAPIEN 3 Resilia valve. Intraoperative pacer malfunction during rapid pacing resulted in valve embolization into the ascending aorta. The valve was maneuvered and repositioned into the descending thoracic aorta, after which a second valve was implanted successfully at the native annulus. The patient subsequently developed new-onset chest and back pain on postoperative day 1. Computed tomography angiography confirmed a DeBakey type B aortic dissection originating at the level of the embolized valve and extending to the diaphragm. A two-step thoracic endovascular aortic repair (TEVAR) was performed using a bare metal Terumo Relay stent to scaffold the embolized valve, followed by a tapered covered stent to seal the dissection. We propose referring to this hybrid approach as the scaffold technique, a novel endovascular strategy to simultaneously stabilize an embolized transcatheter valve and treat coexisting aortic pathology. Valve embolization after TAVR is rare, with an incidence ranging from 0.3% to 1.7%; type B dissection is even more infrequent. The literature supports only a limited number of similar cases managed with TEVAR, and even fewer with a formalized dual-stent strategy, as outlined here. Device selection is critical; TEVAR platforms such as the Terumo Relay, Gore TAG, Medtronic Valiant, and Cook Zenith Alpha each offer unique deployment profiles and structural advantages. This case highlights the importance of rapid recognition, anatomical precision, and endovascular innovation in managing high-risk TAVR complications. This case underscores the vital role of vascular surgery in the contemporary TAVR era. It illustrates the scaffold technique as a safe, effective, and reproducible solution for patients presenting with valve migration, descending thoracic aortic dissection, and limited proximal landing zone where conventional strategies may be insufficient.
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http://dx.doi.org/10.1016/j.jvscit.2025.101926 | DOI Listing |
Future Cardiol
September 2025
Department of Surgery, Harlem Hospital Center, New York, NY, USA.
Introduction: The aim of this article is to compare the long-term efficacy of Thoracic Endovascular Aortic Repair (TEVAR) versus Optimal Medical Therapy (OMT) in reducing mortality among adult patients with uncomplicated Stanford type B aortic dissection (uSTBAD).
Methods: An electronic search of PubMed, Cochrane Central and Google Scholar was conducted for studies comparing TEVAR with OMT for mortality in adult patients with uSTBAD. Relevant outcomes, including mortality, aortic rupture, re-intervention, retrograde type A dissection, myocardial infarction and stroke were analyzed and presented as risk ratios (RRs) along with their 95% confidence intervals (95% CI).
JTCVS Open
August 2025
Division of Cardiovascular Surgery, Department of Surgery, University of Pennsylvania, Philadelphia, Pa.
Objective: Valve selection in acute type A aortic dissection (ATAAD) requiring aortic root replacement is challenging given the clinical acuity, unknown patient preferences, risk of surgical bleeding, and limited life expectancy. We sought to identify long-term outcomes of mechanical versus bioprosthetic aortic root replacement in young patients with ATAAD.
Methods: Retrospective review of our institution's database of ATAAD was conducted to identify patients aged 65 years and younger who underwent mechanical Bentall (mech-Bentall) or bioprosthetic Bentall (bio-Bentall) for ATAAD from 2002 to 2022.
JTCVS Open
August 2025
Department of Anaesthesia and Intensive Care Medicine, Royal Papworth Hospital, Cambridge Biomedical Campus, Cambridge, United Kingdom.
Objective: Postoperative intraluminal thrombosis after frozen elephant trunk replacement has been reported to occur with a frequency of 6% to 17% and is associated with poor outcomes. The purpose of this institutional review is to analyze thrombosis rate, predisposing patient and operative factors, and assess different anticoagulation regimens.
Methods: This retrospective cohort study includes 174 patients operated on over 10 years.
JTCVS Open
August 2025
Department of Cardiothoracic Surgery, Stanford University School of Medicine, Stanford, Calif.
Objectives: Loeys-Dietz syndrome comprises genetically discrete subtypes of varying clinical severity. This study integrates longitudinal Loeys-Dietz syndrome clinical outcomes after aortic root replacement with transcriptomic analysis of aortic smooth muscle cell dysregulation to investigate mechanisms governing this subtype-specific aortic vulnerability.
Methods: Single institutional experience with aortic root replacement for nondissected aneurysm in patients with Loeys-Dietz syndrome was reviewed for midterm survival and distal aortic events (subsequent aortic intervention, aneurysm, or dissection).
JTCVS Open
August 2025
Department of Cardiovascular Surgery, Mayo Clinic, Rochester, Minn.
Objective: To evaluate the early postoperative morbidity, mortality, and prosthetic conduit function of patients who underwent aortic root replacement using a prefabricated bioprosthetic aortic valved conduit.
Methods: Single-center retrospective review of 124 consecutive adult patients who underwent aortic root replacement with a certified prefabricated bioprosthetic aortic valved conduit from 2021 to December 2023.
Results: Indications for operation were aortic aneurysms (n = 92), endocarditis (n = 12), deterioration of prior valve prosthesis (n = 13), and aortic dissection (n = 6).