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Background: Individuals residing in rural areas and those with low socioeconomic status are typically underrepresented in clinical research. Strategies to recruit more representative populations should be explored. This study aimed to compare screening and consenting proportions in a West Virginia-based pregnancy cohort study of individuals sent a recruitment message via the MyChart patient portal, overall and stratified by rurality and insurance status (proxy for socioeconomic status).
Methods: Between October 2022 and April 2023, 1024 recruitment messages were sent via MyChart, a healthcare-affiliated portal. Screening and consenting proportions were calculated overall and stratified by rurality and insurance status. Logistic regression was used to compare participation proportions.
Results: The recruiting method yielded 2.8 % consent. Screening and consenting proportions were similar across stratified groups.
Conclusions: Healthcare-affiliated portals may be a useful strategy to recruit typically underrepresented populations in pregnancy-related research.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12356380 | PMC |
http://dx.doi.org/10.1016/j.conctc.2025.101535 | DOI Listing |
World Neurosurg
September 2025
Department of Neurosurgery, New York University Langone Medical Center, New York, NY.
Objective: Mentorship and training relationships shape the careers and influence of neurosurgeons. Network analysis can reveal structural characteristics and key individuals who support network connectivity and drive the field's development. This endeavor analyzed the US-based neurosurgical training network derived from NeurosurGen.
View Article and Find Full Text PDFLancet Child Adolesc Health
October 2025
Uehiro Oxford Institute, University of Oxford, Oxford, UK; Centre for Biomedical Ethics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
The potential use of psychedelic-assisted therapy for adolescents with mental illness has sparked both interest and concern. Modern psychedelic research has focused on adults, and adolescents younger than 18 years are typically excluded due to ethical and legal challenges. To explore whether adolescents have been included in 21st century psychedelic research, we conducted a scoping review of the medical literature from January, 2000, to April, 2025.
View Article and Find Full Text PDFFront Nutr
August 2025
Department of Nutrition, Dietetics, and Food Sciences, Utah State University, Logan, UT, United States.
Background: Dietary acculturation-the process by which migrants adopt the dietary patterns of their host country-has become increasingly relevant given the unprecedented scale of international migration. This phenomenon is often associated with a shift from traditional diets toward host-country patterns that are higher in ultra processed foods, added sugars, and fats, with potential implications for chronic disease risk.
Objective: This mini-review aims to synthesize global evidence on the dietary transformations experienced by migrant populations and to assess the health implications and modulating factors influencing these changes.
bioRxiv
August 2025
Department of Statistics, University of Illinois Urbana-Champaign.
Spatial transcriptomics (ST) enables gene expression profiling while preserving the spatial architecture of intact tissue. Analyzing ST data often proceeds by first extracting cell-level information, typically through cell segmentation or cell-type deconvolution. However, they can fail to capture important expression patterns, for example from fragile or underrepresented cell types, subcellular structures like neurites, and extracellular expression.
View Article and Find Full Text PDFDementia (London)
August 2025
Canterbury Bankstown Dementia Alliance, NSW, Australia.
Dementia-friendly communities can increase community participation and social wellbeing for people impacted by dementia. However, culturally and linguistically diverse people have typically been excluded or underrepresented from dementia-friendly community design processes. This study aimed to establish the factors that affect community engagement for culturally and linguistically diverse people impacted by dementia, and their suggestions for a dementia-friendly community in Canterbury-Bankstown, Australia.
View Article and Find Full Text PDF