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Article Abstract
Introduction: Sepsis-associated acute kidney injury (SA-AKI) is a frequent complication in critically ill patients and is associated with increased mortality. This study aimed to evaluate the prognostic value of the lactate/albumin ratio (LAR) and other albumin-based biomarkers in predicting SA-AKI.
Methods: A retrospective observational study was conducted on 564 patients with sepsis, divided into two groups based on the presence (n = 298) or absence (n = 266) of AKI. Clinical characteristics, laboratory parameters, and disease severity scores (SOFA, APACHE II, NEWS, NEWS-Lactate) were compared between groups. The predictive performance of each marker in detecting SA-AKI was assessed using receiver operating characteristic (ROC) curve analysis.
Results: serum creatinine/albumin ratio (sCAR), blood urea nitrogen/albumin ratio (BAR), and procalcitonin/albumin ratio (PAR) procalcitonin (PCT)
Conclusion: It seems that, t for early detection of SA-AKI and may outperform conventional severity scores and standalone laboratory parameters.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12341009 | PMC |
| http://dx.doi.org/10.22037/aaemj.v13i1.2723 | DOI Listing |
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