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Taphonomic research aims at reconstructing processes affecting the preservation and modification of paleobiological entities. Recent critiques of the reliability of deep learning (DL) for taphonomic analysis of bone surface modifications (BSMs), such as that presented by Courtenay . based on a selection of earlier published studies, have raised concerns about the efficacy of the method. Their critique, however, overlooked fundamental principles regarding the use of small and unbalanced datasets in DL. By reducing the size of the training and validation sets-resulting in a training set only 20% larger than the testing set, and some class validation sets that were under 10 images-these authors may inadvertently have generated underfit models in their attempt to replicate and test the original studies. Moreover, errors in coding during the preprocessing of images have resulted in the development of fundamentally biased models, which fail to effectively evaluate and replicate the reliability of the original studies. In this study, we do not aim to directly refute their critique, but instead use it as an opportunity to reassess the efficiency and resolution of DL in taphonomic research. We revisited the original DL models applied to three targeted datasets, by replicating them as new baseline models for comparison against optimized models designed to address potential biases. Specifically, we accounted for issues stemming from poor-quality image datasets and possible overfitting on validation sets. To ensure the robustness of our findings, we implemented additional methods, including enhanced image data augmentation, k-fold cross-validation of the original training-validation sets, and a few-shot learning approach using both supervised learning and model-agnostic meta-learning. The latter methods facilitated the unbiased use of separate training, validation, and testing sets. The results across all approaches were consistent, with comparable-if not almost identical-outcomes to the original baseline models. As a final validation step, we used images of recently generated BSM to act as testing sets with the baseline models. The results also remained virtually invariant. This reinforces the conclusion that the original models were not subject to methodological overfitting and highlights their nuanced efficacy in differentiating BSM. However, it is important to recognize that these models represent pilot studies, constrained by the limitations of the original datasets in terms of image quality and sample size. Future work leveraging larger datasets with higher-quality images has the potential to enhance model generalization, thereby improving the applicability and reliability of DL approaches in taphonomic research.
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http://dx.doi.org/10.1093/biomethods/bpaf057 | DOI Listing |
J Neurooncol
September 2025
Institute of Medical Biostatistics, Epidemiology, and Informatics (IMBEI), University Medical Center Mainz, Mainz, Germany.
Purpose: Patients diagnosed with high-grade gliomas (HGG) often experience substantial psychosocial dis-tress. However, due to neurological and neurocognitive deficits its assessment remains challenging, and needs remain unmet. We compared a novel face-to-face assessment during doctor-patient conversations with questionnaire-based screening.
View Article and Find Full Text PDFJ Math Biol
September 2025
Department of Mathematics, Texas A&M University, Mailstop 3368, College Station, TX, 77843-3368, United States.
We study how environmental stochasticity influences the long-term population size in certain one- and two-species models. The difficulty is that even when one can prove that there is coexistence, it is usually impossible to say anything about the invariant probability measure which describes the coexisting species. We are able to circumvent this problem for some important ecological models by noticing that the per-capita growth rates at stationarity are zero, something which can sometimes yield information about the invariant probability measure.
View Article and Find Full Text PDFAesthetic Plast Surg
September 2025
Department of Plastic Surgery, The First Affiliated Hospital, Jinan University, No. 613 West, Huangpu Avenue, Guangzhou, 510630, Guangdong Province, China.
Background: Microfocused ultrasound (MFU) is a non-invasive technique used for facial rejuvenation, yet there is limited quantitative data on its long-term effects. This study aimed to evaluate the long-term efficacy and safety of MFU for facial rejuvenation. We utilized standardized photography along with advanced skin assessment technologies to analyze the impact of MFU on facial morphology, skin function, and patient satisfaction over a 12-month period.
View Article and Find Full Text PDFEur J Nutr
September 2025
Institute of Public Health and Clinical Nutrition, University of Eastern Finland, PO Box 1627, 70211, Kuopio, Finland.
Purpose: To investigate how a group-based lifestyle intervention affects food choices and if the dietary patterns at the end of the intervention are associated with incidence type 2 diabetes (T2D). We also investigated if the possible associations between diet and T2D risk were modified by the genetic risk for T2D.
Methods: Participants in the T2D-GENE study were men with prediabetes aged 50-75 years, body mass index ≥ 25 kg/m, belonging in either low or high genetic risk score (GRS) tertile for T2D.
Perfusion
September 2025
Cardiac Surgery Department, Bristol Royal Children's Hospital, Bristol, UK.
BackgroundDuring cardiopulmonary bypass (CPB), goal-directed perfusion (GDP) seeks to match oxygen delivery to metabolic demand, but the dynamics of oxygen extraction and intraoperative oxygen demand remain poorly understood, especially in paediatric populations. Existing models rely on limited data and assume, for example, a linear relationship between log oxygen demand and temperature.MethodsWe developed GARIX (Global AutoRegressive Integrated model with eXogenous variables and an equilibrium force) to predict minute-by-minute changes in oxygen extraction ratio (OER) using high-resolution intraoperative data.
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