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Article Abstract
Objectives: This study aimed to identify imaging features of IgG4-related sialadenitis (IgG4-RS) and differentiate it from Sjögren's syndrome (SS) and chronic obstructive parotid/submandibular sialadenitis (COP/COS).
Study Design: A retrospective analysis of sialographic findings was conducted on 40 IgG4-RS patients. Two radiologists blindly evaluated sialographic features, including ductal dilation, wall smoothness, duct interruption, acinar patterns, and glandular emptying. A comparative analysis with SS and COP/COS was also performed.
Results: Sialograms of 40 IgG4-RS patients (82 glands), 61 SS patients (71 glands), and 69 COP/COS patients (95 glands) were analyzed. Sialographic findings were categorized into four types: Type I (diminished/interrupted ducts without dilation), Type II (diminished/interrupted ducts with dilation), Type III (dilated main/branch ducts), and Type IV (normal appearance). In IgG4-RS, Type I and III were predominant in parotid glands, while Type I was more frequent in submandibular glands. Type II was most common in SS, and Type III in COP/COS.
Conclusions: Sialography reveals distinct features in IgG4-RS, especially in submandibular glands, characterized by diminished or interrupted secondary and tertiary ducts without peripheral duct dilation, aiding differentiation from SS and COP/COS.
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| http://dx.doi.org/10.1016/j.oooo.2025.07.005 | DOI Listing |
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