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Background: In recent years, the concept of adaptive interventions (AIs) has attracted the attention of researchers in the medical field. Our study aimed to visualize the publications to determine the hotspots and frontiers in research on AIs and provide guidance and reference for further study.
Methods: We searched the Web of Science Core Collection up to December 2024, and only articles and review articles about AIs were included. The countries of origin, authors, co-citation references, hotspots, and frontier were analyzed by VOSviewer V.1.6.20, CiteSpace V.5.7.R5, and Scimago Graphica.
Results: A total of 429 publications were identified, including 399 original studies and 30 reviews. The number of studies has proliferated since 2016. The United States, especially the University of Michigan, made significant contributions to this field. There was a closer collaboration among author teams and more frequent AIs research development and collaboration in Europe, the United States, and Australia. Just-in-time adaptive interventions are the predominant intervention design of concern at this stage, with addictive behavior and mental health as the main fields of research in medicine. AIs utilizing mobile health, combining ecological momentary assessment tools, may represent an emerging trend in future research.
Conclusion: Researchers' understanding of AIs has improved dramatically over the past 20 years. At present, the emphasis of research on AIs is gradually transitioning from initial theoretical development to practical application and effectiveness evaluation, and we look forward to seeing it applied in more areas.
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http://dx.doi.org/10.1093/tbm/ibaf037 | DOI Listing |
Cereb Cortex
August 2025
Nencki Institute of Experimental Biology, PAS, 3 Pasteur Street, 02-093 Warsaw, Poland.
In the visual cortices, receptive fields (RFs) are arranged in a gradient from small sizes in the center of the visual field to the largest sizes at the periphery. Using functional magnetic resonance imaging (fMRI) mapping of population RFs, we investigated RF adaptation in V1, V2, and V3 in patients after long-term photoreceptor degeneration affecting the central (Stargardt disease [STGD]) and peripheral (Retinitis Pigmentosa [RP]) regions of the retina. In controls, we temporarily limited the visual field to the central 10° to model peripheral loss.
View Article and Find Full Text PDFInfect Immun
September 2025
School of Veterinary Medicine and Biomedical Sciences, University of Nebraska, Lincoln, Nebraska, USA.
Cell death mechanisms play a fundamental role in mycobacterial pathogenesis. We critically reviewed 94 research manuscripts, 44 review articles, and 4 book chapters to analyze important discoveries, background literature, and potential shortcomings in the field. The focus of this review is the pathogen (Mtb) and other Mtb and complex microorganisms.
View Article and Find Full Text PDFInt J Comput Assist Radiol Surg
September 2025
Institute of Computer Science, Friedrich-Schiller-Universität, Fürstengraben 1, 07743, Jena, Thuringia, Germany.
Purpose: Cerebral aneurysms are blood-filled bulges that form at weak points in blood vessel walls, and their rupture can lead to life-threatening consequences. Given the high risk associated with these aneurysms, thorough examination and analysis are essential for determining appropriate treatment. While existing tools such as ANEULYSIS and its web-based counterpart WEBANEULYSIS provide interactive means for analyzing simulated aneurysm data, they lack support for collaborative analysis, which is crucial for enhancing interpretation and improving treatment decisions in medical team meetings.
View Article and Find Full Text PDFMed Oncol
September 2025
Venom and Biotherapeutics Molecules Laboratory, Biotechnology Department, Biotechnology Research Center, Pasteur Institute of Iran, Tehran, Iran.
Neuropeptide Y (NPY) and the voltage-gated potassium channel Kv1.3 are closely associated with breast cancer progression and apoptosis regulation, respectively. NPY receptors (NPYRs), which are overexpressed in breast tumors, contribute to tumor growth, migration, and angiogenesis.
View Article and Find Full Text PDFIn Vitro Cell Dev Biol Anim
September 2025
Department of Cell Biology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, 2-5-1 Shikata-cho, Kita-ku, Okayama-shi, Okayama, 700-8558, Japan.
S100 protein family members S100A8 and S100A9 function primarily as a heterodimer complex (S100A8/A9) in vivo. This complex has been implicated in various cancers, including gastric cancer (GC). Recent studies suggest that these proteins play significant roles in tumor progression, inflammation, and metastasis.
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