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Accurate segmentation and classification of liver tumors are crucial for early diagnosis and effective treatment planning. However, conventional deep learning models such as tumor heterogeneity, class imbalance, and high computational demands face challenges, limiting their clinical deployment. This study introduces a lightweight hybrid framework combining an optimized Swin-UNet for segmentation with a Quantum Convolutional Neural Network (QCNN) for classification. The Swin-UNet is enhanced using a metaheuristic Search and Rescue (SAR) algorithm and a quadratic penalty-based objective function to balance compactness and accuracy. A Focal AUC loss function addresses class imbalance and improves sensitivity to minority regions. The QCNN leverages quantum-inspired mechanisms such as entanglement and superposition to achieve superior performance with reduced parameters. Evaluated on three benchmark datasets (3D-IRCADb, LiTS17, and MSD Task03), the framework achieves Dice scores of 85.8%, 88.7%, and 88.4%, respectively, alongside 96.7% classification accuracy. The model size is reduced to 64.16 MB, enabling real-time inference on edge devices (Jetson Nano). The QCNN classifier outperforms traditional CNNs in all metrics, demonstrating its effectiveness in high-dimensional medical data analysis. This work bridges the gap between diagnostic precision and computational efficiency, presenting a clinically viable AI solution for liver tumor analysis.
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http://dx.doi.org/10.1007/s10278-025-01630-3 | DOI Listing |
Basic Clin Pharmacol Toxicol
October 2025
Amity Institute of Biotechnology, Amity University, Noida, Uttar Pradesh, India.
Early detection of diseases is a critical pillar in advancing modern healthcare, offering timely interventions and better patient outcomes. This overview highlights a range of machine learning (ML) approaches that are transforming early disease diagnosis. We discuss how traditional supervised and unsupervised methods, alongside advanced deep learning and reinforcement learning techniques, are utilized to detect early disease markers, often before clinical symptoms appear.
View Article and Find Full Text PDFSmall Methods
September 2025
School of Mechanical Engineering, Sungkyunkwan University, Suwon, 16419, South Korea.
Droplet generation has been utilized in various applications, including drug delivery, the fabrication of functional particles, and material synthesis. Achieving the goals of these applications requires droplet generation of a desired size. Microfluidic droplet generation offers precise control of droplet dimensions.
View Article and Find Full Text PDFAdv Sci (Weinh)
August 2025
Shenyang National Laboratory for Materials Science, Institute of Metal Research, Chinese Academy of Sciences, Shenyang, 110016, China.
Nonvolatile optoelectronic synapses motivated by the human eye can effectively function as convolutional kernels to preprocess images, demonstrating significant promise for edge computing. Among the optoelectronic synapses, the floating-gate photosensitive transistor (FG-PT) is particularly noteworthy due to its rapid response speed and excellent retention. Although some FG-PTs are reported, they still suffer from high operating voltages, low conductance ratios, and difficulties in array preparation.
View Article and Find Full Text PDFSci Rep
August 2025
Department of Computer Science, University of Tsukuba, Tsukuba, 3058577, Japan.
Deep learning has achieved significant success in pattern recognition, with convolutional neural networks (CNNs) serving as a foundational architecture for extracting spatial features from images. Quantum computing provides an alternative computational framework, a hybrid quantum-classical convolutional neural networks (QCCNNs) leverage high-dimensional Hilbert spaces and entanglement to surpass classical CNNs in image classification accuracy under comparable architectures. Despite performance improvements, QCCNNs typically use fixed quantum layers without incorporating trainable quantum parameters.
View Article and Find Full Text PDFEntropy (Basel)
July 2025
Key Laboratory of Advanced Transducers and Intelligent Control System, Ministry of Education, Taiyuan University of Technology, Taiyuan 030024, China.
Secure communication is critically dependent on high-speed and high-security quantum random number generation (QRNG). In this work, we present a responsive approach to enhance the efficiency and security of QRNG by leveraging polarization-controlled heterodyne detection to simultaneously measure the quadrature amplitude and phase fluctuations of vacuum shot noise. To address the practical non-idealities inherent in QRNG systems, we investigate the critical impacts of imbalanced heterodyne detection, amplitude-phase overlap, finite-size effects, and security parameters on quantum conditional min-entropy derived from the entropy uncertainty principle.
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