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A high-temperature-resistant gas pressure sensor based on an all-silica Fabry-Perot interferometer (FPI) structure is proposed. A carbon dioxide () laser is utilized to achieve integrated welding between a silica capillary tube and optical fibers. A cascaded femtosecond laser-inscribed fiber Bragg grating is used to compensate for the influence of temperature. The cavity length of the FPI is linearly correlated with gas pressure. Therefore, the pressure can be measured by analyzing the optical path difference of the FPI. Experimental results demonstrate that the sensor exhibits good linearity within a pressure range of 0-14 MPa, with a sensitivity of 58 nm/MPa and an error of 0.8% full scale (F.S.). It can measure 0-3.2 MPa gas pressure stably in an environment of 25-655°C. The sensor features a compact structure and shows broad application prospects in fields such as safety monitoring, energy power, and geological exploration.
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http://dx.doi.org/10.1364/AO.565014 | DOI Listing |
Curr Drug Metab
September 2025
First School of Clinical Medicine, Yunnan University of Chinese Medicine, Kunming 650500, China.
Background: Tetrandrine (TET) demonstrates therapeutic potential for hypoxic pulmonary hypertension (HPH); however, its precise pharmacological mechanisms remain unclear. In this study, we aimed to investigate the effects of TET on pulmonary vascular remodeling (PVR) in HPH and elucidate the molecular pathways through which TET ameliorates HPH.
Methods: We established a rat model of HPH and evaluated the therapeutic effects of TET by measuring hemodynamic parameters, assessing right ventricular hypertrophy, and analyzing pathological changes in lung tissue.
Biomater Adv
September 2025
Department of Applied Science and Technology (DISAT), Politecnico di Torino, Corso Duca Degli Abruzzi 24, 10129 Torino, Italy.
Tailoring surface characteristics is key to guiding scaffold interaction with the biological environment, promoting successful biointegration while minimizing immune responses and inflammation. In cardiac tissue engineering, polyvinylidene fluoride (PVDF) is a material of choice for its intrinsic piezoelectric properties, which can be enhanced through electrospinning, also enabling the fabrication of nanofibrous structures mimicking native tissue. However, the inherent hydrophobicity of PVDF can hinder its integration with biological tissues.
View Article and Find Full Text PDFChem Asian J
September 2025
Interdisciplinary Research Centre for Membranes and Water Security, King Fahd University of Petroleum and Minerals, Dhahran, 31261, Saudi Arabia.
In this study, a silicon carbide (SiC) mixed-matrix membrane for oil-water separation was successfully fabricated within the nanofiltration range. Silicon carbide was synthesized using rice husk ash (RHA), an agricultural waste material, combined with polydimethylsiloxane (PDMS) and subsequently incorporated into a mixed matrix membrane for oil-water separation. Polysulfone (PSF) and polyvinylpyrrolidone (PVP) were employed as polymer supports for fabricating the SiC-based mixed matrix membrane, which was tested in a dead-end filtration setup.
View Article and Find Full Text PDFJ Physiol
September 2025
Institue for Exercise and Environmental Medicine, Texas Presbyterian Hospital, Dallas, TX, USA.
Some patients with heart failure with preserved ejection fraction (HFpEF) have demonstrated evidence of exercise-induced arterial hypoxaemia (EIAH). However, EIAH was not quantified using , , and measurements as previously conducted in healthy adults nor was EIAH quantified alongside simultaneous measurements of pulmonary vascular pressures, cardiorespiratory responses, or dyspnoea on exertion (DOE) in these patients. Given the effects of hypoxaemia on pulmonary vasoconstriction, cardiorespiratory responses, and DOE, we tested the hypothesis that patients with HFpEF and EIAH (EIAH) would demonstrate higher pulmonary vascular pressures, worse oxygen uptake, and greater DOE compared with patients without EIAH (EIAH).
View Article and Find Full Text PDFJ Biomech Eng
September 2025
Department of Chemical and Biomolecular Engineering, University of Deleware, Newark, Delaware USA.
The beauty of the respiratory system is that it advects air from the mouth/nose to the deep lung, providing a substrate for the gas exchange needed for life. Due to the close interaction of structure and function, the lungs can deform under very small amounts of pressure. In addition, the lung serves as the first barrier of defense against inhaled toxins.
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