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() keratitis is a rare, sight-threatening infection primarily seen in contact lens users. A 22-year-old female developed sudden ocular symptoms two days after contact lens use. Examination revealed significant conjunctival injection, anterior chamber inflammation, and a corneal abscess with an epithelial defect. Despite initial moxifloxacin treatment, her condition worsened, requiring a switch to fortified vancomycin, ceftriaxone, and voriconazole. Cultures confirmed , allowing treatment to be streamlined to fortified ceftriaxone. The infection gradually resolved, with visual acuity returning to 20/20 and minimal residual scarring noted at one month.
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http://dx.doi.org/10.2147/OPTO.S535720 | DOI Listing |
Anat Sci Educ
September 2025
Human Anatomy, Vita-Salute San Raffaele University, Milan, Italy.
As emerging technologies reshape both the body and how we represent it, anatomical education stands at a threshold. Virtual dissection tools, AI-generated images, and immersive platforms are redefining how students learn anatomy, while real-world bodies are becoming hybridized through implants, neural interfaces, and bioengineered components. This Viewpoint explores what it means to teach human anatomy when the body is no longer entirely natural, and the image is no longer entirely real.
View Article and Find Full Text PDFEye Contact Lens
September 2025
Department of Ophthalmology, Mayo Clinic Alix School of Medicine (H.P.N.), Mayo Clinic in Arizona, Scottsdale, AZ; and Department of Ophthalmology (O.M.H., D.R.P., E.R.K., J.F.S.), Mayo Clinic in Arizona, Scottsdale, AZ.
This case series reports two cases of scleral lens (SL)-associated suture erosion of polytetrafluoroethylene CV-8 (Gore-Tex, Newark, DE) in scleral-sutured CZ70BD (Alcon, Fort Worth, TX) posterior chamber intraocular lens (SS-PCIOL). Suture erosion after SS-PCIOL has been reported in two of the patients who were fitted with SL for visual acuity improvement. Erosion was corrected in both cases with suture repositioning and corneal patch graft, with one patient requiring the exchange of the intraocular lens.
View Article and Find Full Text PDFUnlabelled: Contact lens wear in humans and mice is consistently associated with asymptomatic corneal parainflammation. Here, we tested the hypothesis that the corneal response to lens wear alone can function to protect it against bacterial adhesion enabled by superficial injury. One eye only of mT/mG-LysMcre mice (cell membranes red; Lyz2 cells green) wore a contact lens for 4-6 days.
View Article and Find Full Text PDFClin Ophthalmol
August 2025
Centre for Ocular Research & Education (CORE), School of Optometry & Vision Science, University of Waterloo, Waterloo, ON, Canada.
Purpose: To evaluate the effectiveness of lifitegrast ophthalmic solution 5% in alleviating end-of-day dryness and discomfort in symptomatic contact lens (CL) wearers.
Patients And Methods: This was an open-label study in symptomatic CL wearers with ratings of ≥40 for end-of-day dryness on a visual analog scale (VAS; 0-100 scale; 100 worst). Participants wore their habitual CLs and instilled lifitegrast twice daily for 12 weeks with lenses removed.
Clin Ophthalmol
August 2025
Department of Ophthalmology and Visual Sciences, University of British Columbia, Vancouver, BC, Canada.
Purpose: This study aims to evaluate rotational stability and patient-reported outcomes associated with Tecnis Eyhance toric II "monofocal plus" intraocular lens (IOL), particularly in light of a modified haptic design.
Methods: A prospective, interventional study was conducted with patients undergoing routine cataract surgery and Tecnis Eyhance toric II IOL implantation. The inclusion criteria were topographic corneal astigmatism of 0.