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This study investigates emergent behaviors in multi-agent pursuit-evasion games within a bounded 2D grid world, where both pursuers and evaders employ multi-agent reinforcement learning (MARL) algorithms to develop adaptive strategies. We define six fundamental pursuit actions-flank, engage, ambush, drive, chase, and intercept-which combine to form 21 types of composite actions during two-pursuer coordination. After training with MARL algorithms, pursuers achieved a 99.9% success rate in 1,000 randomized pursuit-evasion trials, demonstrating the effectiveness of the learned strategies. To systematically identify and measure emergent behaviors, we propose a K-means-based clustering methodology that analyzes the trajectory evolution of both pursuers and evaders. By treating the full set of game trajectories as statistical samples, this approach enables the detection of distinct behavioral patterns and cooperative strategies. Through analysis, we uncover emergent behaviors such as lazy pursuit, where one pursuer minimizes effort while complementing the other's actions, and serpentine movement, characterized by alternating drive and intercept actions. We identify four key cooperative pursuit strategies, statistically analyzing their occurrence frequency and corresponding trajectory characteristics: serpentine corner encirclement, stepwise corner approach, same-side edge confinement, and pincer flank attack. These findings provide significant insights into the mechanisms of behavioral emergence and the optimization of cooperative strategies in multi-agent games.
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http://dx.doi.org/10.1038/s41598-025-15057-x | DOI Listing |
J Sep Sci
September 2025
Department of Analytical Chemistry, Faculty of Science, Palacký University Olomouc, Olomouc, Czech Republic.
The increasing use of engineered nanoparticles (NPs) in consumer and biomedical products has raised concern over their potential accumulation, transformation, and toxicity in biological systems. Accurate analytical methods are essential to detect, characterize, and quantify NPs in complex biological matrices. Inductively coupled plasma mass spectrometry (ICP-MS) has emerged as a leading technique due to its high sensitivity, elemental selectivity, and quantitative capabilities.
View Article and Find Full Text PDFBMC Psychiatry
September 2025
Zentrum Isartal Am Kloster Schäftlarn, Schäftlarn, Germany.
Background: Patients with mental health conditions represent a significant concern in emergency departments, consistently ranking as the third or fourth most prevalent diagnoses during consultations. Globally, over the past two decades, there was a marked increase in such incidences, largely driven by a rise in nonurgent visits related to somatic complaints. However, the implications of these nonurgent visits for mental health patients remain unclear, and warrant further investigation.
View Article and Find Full Text PDFStem Cell Rev Rep
September 2025
Department of Medical Genetics and Prenatal Diagnostics, The Third Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
The emergence of organoid models has significantly bridged the gap between traditional cell cultures/animal models and authentic human disease states, particularly for genetic disorders, where their inherent genetic fidelity enables more biologically relevant research directions and enhances translational validity. This review systematically analyzes established organoid models of genetic diseases across organs (e.g.
View Article and Find Full Text PDFEnviron Monit Assess
September 2025
College of Ecological and Environmental Engineering, Guizhou Minzu University, Guiyang, 550025, China.
The rapid development of industry and agriculture has led to a significant increase in the toxicity and pollution of cadmium (Cd) and lead (Pb) in soil. Consequently, soil remediation employing biochar or modified biochar has emerged as a cost-effective and environmentally sustainable approach to address the issue of heavy metal (HM) ion pollution. PEI-functionalization biochar (PBC) derived from corn straw (PBCC), wood straw (PBCW), and rice straw (PBCR) was synthesized to immobilize Cd and Pb in contaminated acidic yellow soil.
View Article and Find Full Text PDFNat Rev Microbiol
September 2025
National Centre for Antimicrobial Stewardship, Department of Infectious Diseases, Melbourne Medical School, The University of Melbourne, Carlton, Victoria, Australia.
The global rise of antimicrobial resistance (AMR) poses a profound threat to human, animal and environmental health. Although antimicrobials have revolutionized modern medicine, their overuse and misuse have accelerated AMR, necessitating urgent, multisectoral action. Antimicrobial stewardship (AMS), a set of coordinated strategies that promote responsible antimicrobial use, has emerged as a key intervention in managing AMR.
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