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http://dx.doi.org/10.1136/jech-2025-224358 | DOI Listing |
JMIR Ment Health
September 2025
Department of Psychology, University of California, Los Angeles, 1285 Franz Hall, Box 951563, Los Angeles, CA, 90095, United States, 1 3107941262.
Background: Youth mental health issues have been recognized as a pressing crisis in the United States in recent years. Effective, evidence-based mental health research and interventions require access to integrated datasets that consolidate diverse and fragmented data sources. However, researchers face challenges due to the lack of centralized, publicly available datasets, limiting the potential for comprehensive analysis and data-driven decision-making.
View Article and Find Full Text PDFJMIR Hum Factors
September 2025
College of Biomedical Engineering & Instrument Science, Zhejiang University, Hangzhou, China.
Background: The rapid advancement of next-generation sequencing has significantly expanded the landscape of precision medicine. However, health care professionals face increasing challenges in keeping pace with the growing body of oncological knowledge and integrating it effectively into clinical workflows. Precision oncology decision support (PODS) tools aim to assist clinicians in navigating this complexity, yet their current functionalities only partially address clinical needs.
View Article and Find Full Text PDFPLoS One
September 2025
Department of Internal Medicine, School of Medical Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
In resource-limited settings in Africa, which harbour the greatest burden of Sickle Cell Disease (SCD) globally, poor care outcomes are driven in part, by a lack of trained healthcare providers (HCP) and an absence of context-specific treatment guidelines appropriate to the level of healthcare facility. The study aimed to evaluate the impact of a structured training program on HCP's knowledge of SCD in Ghana. This was prospective cross-sectional study involving HCPs from 46 health facilities from 4 out of 16 regions in Ghana.
View Article and Find Full Text PDFPLoS One
September 2025
School of Psychology, Queens University Belfast, Belfast, Northern Ireland, United Kingdom.
Objectives: Individuals with dementia often experience stigmatisation and social exclusion. To develop dementia-friendly communities, it is important to take a life-course approach to enhance the perception of dementia in the general population. Currently, we lack an overall understanding of adolescent perceptions of dementia.
View Article and Find Full Text PDFJ Vis Exp
August 2025
Molemuse Biotech Studio;
Mass spectrometry (MS)-based proteomics data, including Data-Dependent Acquisition (DDA) and Data-Independent Acquisition (DIA), are widely used in biological research. However, the application of these datasets in validation studies is still limited due to the lack of clear demonstrations on how to effectively search and analyze proteomic data. To fill this gap, we selected one DDA and one DIA dataset deposited in the PRoteomics IDEntifications Database (PRIDE) data repository to better illustrate the proteomic data analysis workflow and downstream post-processing of protein search results.
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