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Article Abstract
In the current study, a new polysaccharide named Bletilla striata polysaccharide (BSP) with an average molecular weight ( ) of 85.4 kDa was obtained from The inhibitory effects of BSP on α-amylase and α-glucosidase, as well as its prebiotic properties, were determined. The results showed that BSP was a neutral polysaccharide and is composed of mannose, glucose, and galactose with a relative molar ratio of 3.2:5.4:1.0. The main sugar residues in BSP were →4)-α-D-Glc-(1→, →6)-β-D-Gal-(1→, →4)-β-D-Man-(1→, and β-D-Man-(1→. BSP displayed strong inhibitory effects against α-amylase and α-glucosidase and exhibited competitive inhibitory kinetics. At 4.0 mg/mL, the inhibitory rates of 67.75 ± 0.45% on α-amylase and 48.24 ± 1.02% on α-glucosidase were obtained, respectively. Moreover, BSP can serve as a carbon source to facilitate the proliferation of probiotics. These findings support the potential application of BSP in diabetes management.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12331579 | PMC |
| http://dx.doi.org/10.3389/fnut.2025.1625260 | DOI Listing |
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