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Treacher-Collins syndrome (TCS) presents significant challenges in airway management due to craniofacial abnormalities that often worsen with age. We describe the anesthetic management of a three-year-old male with TCS and no history of corrective surgery. Ketamine was used to facilitate vascular access and achieve adequate anesthetic depth. After three unsuccessful intubation attempts, an adult-sized Ovassapian airway was employed to guide a fiberoptic bronchoscope beneath the epiglottis and through the vocal cords, resulting in successful intubation. Postoperative airway management was optimized through multidisciplinary collaboration, highlighting the importance of preoperative planning and team-based decision-making in complex pediatric airway cases.
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http://dx.doi.org/10.7759/cureus.87655 | DOI Listing |
Respir Care
September 2025
Dr. Thomasian and Prof. Wunsch are affiliated with Department of Anesthesiology, Weill Cornell Medicine, New York, New York, USA.
Negative-pressure ventilation (NPV) is a form of noninvasive respiratory support in which an external subatmospheric pressure is applied to the thorax to facilitate lung expansion. Although largely supplanted by positive-pressure ventilation (PPV) in modern-day practice, NPV has garnered renewed interest as a potential noninvasive adjunct or alternative to PPV. Appropriate patient selection would be key, particularly in the ICU setting, where NPV is generally contraindicated in patients with severe upper airway obstruction, high oxygenation requirements, or absent airway reflexes.
View Article and Find Full Text PDFSemin Ultrasound CT MR
September 2025
Department of Radiology, University of North Carolina at Chapel Hill, Chapel Hill, NC. Electronic address:
Fetal magnetic resonance imaging (MRI) is a safe method of in-utero evaluation of fetal anomalies and a valuable adjunct to prenatal ultrasound. The utilization of rapid sequences reduces the impact of fetal motion and allows for high contrast resolution of fetal structures. A thorough understanding of fetal anatomy and a systematic approach to MRI interpretation are essential for accurate diagnosis of fetal head and neck anomalies.
View Article and Find Full Text PDFCrit Care Sci
September 2025
Universitätsklinikum Carl Gustav Carus - Dresden, Sachsen, Germany.
The PROtective VEntilation (PROVE) Network is a globally-recognized collaborative research group dedicated to advancing research, education, and collaboration in the field of mechanical ventilation. Established to address critical questions in intraoperative and intensive care ventilation, the network focuses on improving outcomes for patients undergoing mechanical ventilation in diverse settings, including operating rooms, intensive care units, burn units, and resource-limited environments in low- and middle-income countries. The PROVE Network is committed to generating high-quality evidence through a comprehensive portfolio of investigations, including randomized clinical trials, observational research, and meta-analyses.
View Article and Find Full Text PDFSci Transl Med
September 2025
Department of Mechanical Engineering, University of California, Santa Barbara, Santa Barbara, CA 93106, USA.
Endotracheal intubation is a critical medical procedure for protecting a patient's airway. Current intubation technology requires extensive anatomical knowledge, training, technical skill, and a clear view of the glottic opening. However, all of these may be limited during emergency care for trauma and cardiac arrest outside the hospital, where first-pass failure is nearly 35%.
View Article and Find Full Text PDFSleep Breath
September 2025
School of medicine, Università Campus Bio-Medico di Roma, Rome, Italy.
Introduction: It is well known that Obstructive Sleep Apnea (OSA) is a complex disease characterized by an Upper Airway (UA) collapse during sleep, with potential consequences on ENT districts. Recent evidence suggests a possible association with Eustachian Tube Dysfunction (ETD). However, the potential effects of both surgical and non-surgical therapeutic strategies on ET function remain poorly explored in the current literature.
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