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Aim Of The Study: This study focused on the first link of the chain of survival by examining the dispatcher's ability to early recognition of the OHCA patient and assessing patient outcomes.
Methods: This was a prospective cohort study that included patients who suffered OHCA in Pirkanmaa Finland in 2022. Two researchers listened to all calls separately determining key-time events of the call. All patients with confirmed recognisable OHCA during the call who had background data and audio recordings available were included.
Results: We received 451 recordings, 246 of which met the inclusion criteria, and 217 (88 %) were recognised as OHCA. The beginning of tele-CPR guidance (1 min 20 sec vs 1 min 55 sec, p = 0.002) and initiation of bystander CPR (2 min 48 sec vs 3 min 50 sec, p = 0.012) were faster in cases with shockable rhythm on EMS arrival. Every minute of delay in the dispatcher initiating tele-CPR guidance decreased the probability of shockable initial rhythm by 23 % (OR 0.76 [0.61;0.95], p = 0.018). Shockable initial rhythm was more common among patients who were alive at three months after OHCA (83 % vs 21 %, p < 0.001). In multivariable analysis, shockable initial rhythm favoured 3-month survival (OR 16.67 [5.41;52.63], p < 0.001). Overall survival at three months was 12 % (29/246), of which 90 % (26/29) had a Cerebral Performance Category of 1-2.
Conclusion: Quick tele-CPR guidance may be related to/ associated with improving the chances for shockable initial rhythm, thus further improving the chances for long-term survival.
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http://dx.doi.org/10.1016/j.resuscitation.2025.110755 | DOI Listing |
Clin Neurol Neurosurg
September 2025
Department of Neurology, UPMC, Pittsburgh, PA, USA. Electronic address:
Background: Final infarct volume (FIV) is a strong predictor of stroke outcomes. Although smaller FIV are associated with better outcomes, many patients fail to achieve functional independence. We aimed to identify poor outcome predictors in patients with anterior large vessel occlusion stroke (LVOS) who underwent mechanical thrombectomy (MT) and had small FIV.
View Article and Find Full Text PDFNutr Clin Pract
September 2025
Nutrition Department, Faculty of Medicine, Federal University of Rio Grande do Sul, Porto Alegre, Brazil.
Background: Early diagnosis of malnutrition is essential for rapid decision-making regarding nutrition care to improve patient outcomes. We aimed to evaluate the prevalence of malnutrition using the Global Leadership Initiative on Malnutrition (GLIM) criteria and to assess the association of GLIM with 1-year mortality and length of hospital stay (LOS) in patients admitted to an emergency department (ED).
Methods: Prospective cohort study conducted in the ED of a university hospital.
World J Surg Oncol
September 2025
Department of Urology, The Affiliated Hospital of Qingdao University, Qingdao, China.
Background: Inflammation impacts the prognosis of numerous types of tumors. Inflammatory indicators such as the neutrophil-to-lymphocyte ratio, lymphocyte-to-monocyte ratio, and neutrophil-to-eosinophil ratio (NER) have emerged as potential prognostic markers and are closely correlated with the outcomes of cancer patients. However, the connection between NER and cancer prognosis remains incompletely understood.
View Article and Find Full Text PDFMol Psychiatry
September 2025
Department of Child and Adolescent Psychiatry and Psychology, Erasmus MC University Medical Center Rotterdam, Rotterdam, the Netherlands.
Epigenetic processes, such as DNA methylation, show potential as biological markers and mechanisms underlying gene-environment interplay in the prediction of mental health and other brain-based phenotypes. However, little is known about how peripheral epigenetic patterns relate to individual differences in the brain itself. An increasingly popular approach to address this is by combining epigenetic and neuroimaging data; yet, research in this area is almost entirely comprised of cross-sectional studies in adults.
View Article and Find Full Text PDFBr J Anaesth
September 2025
Tissue Repair and Regeneration Laboratory (TR2Lab), Institut de Recerca i Innovació en Ciències de la Vida i la Salut a la Catalunya Central (IrisCC), Vic, Barcelona, Spain; Department of Internal Medicine, Hospital d'Olot i comarcal de la Garrotxa, Olot, Girona, Spain; Faculty of Medicine, Univer