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Purpose: To assess the contribution of each optional parameter to the IOL power calculation and evaluate the effect of omitting biometric variables (ACD, LT, WTW) using the VRF-G formula.
Methods: A total of 501 eyes from 501 consecutive patients included in the study underwent cataract surgery with in-the-bag implantation of one-piece soft hydrophobic acrylic posterior chamber IOLs, AcrySof IQ SN60WF (Alcon Labs, Fort Worth, TX, USA). The primary calculation comprised five measured variables, and IOL power was recalculated for different combinations of omitting ACD, LT, and WTW. Outcome measurements included the difference in IOL power calculations between different omission combinations.
Results: Omitting any of the biometric variables resulted in a significant difference in the mean difference in IOL power calculation (ranging from 0.029 to 0.108 diopters), except for WTW omission alone (0.002 diopters). ACD proved to have the most impact, with its omission resulting in larger differences in power calculations (range: 0.177-0.248 diopters) compared to combinations where ACD was not omitted (range: 0.057-0.141 diopters). The shortest eyes were most affected by ACD omission.
Conclusion: The study highlights the importance of ACD in IOL power calculations, particularly for shorter eyes. WTW and LT were found to be less important when using the VRF-G formula for IOL power calculations.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12327424 | PMC |
http://dx.doi.org/10.2147/OPTH.S537931 | DOI Listing |
J Cataract Refract Surg
July 2025
Helsinki Retina Research Group, University of Helsinki, Finland.
Topic: To compare the outcomes of surgical approaches to correct ametropia following cataract and lens surgery.
Clinical Relevance: Despite advancements in the field of biometry and intraocular lens (IOL) power calculation formulas, complete elimination of refractive surprises following cataract and lens surgery is impossible. Preferred Practice Patterns acknowledges the possibility of refractive surprise following cataract surgery; however, no recommendations regarding the preferred treatment have been given.
J Refract Surg
September 2025
From the Department of Ophthalmology, Goethe-University, Frankfurt am Main, Germany and.
Purpose: To evaluate intraocular lens (IOL) power calculation of a non-diffractive extended depth of focus (EDOF) IOL after myopic laser in situ keratomileusis (LASIK) without historical data.
Methods: In this consecutive case series, patients who had undergone lens surgery with implantation of a non-diffractive EDOF IOL after myopic laser in situ keratomileusis (LASIK) at the Department of Ophthalmology, University Hospital Frankfurt, Frankfurt, Germany, were included. Preoperative assessments included biometry and tomography using Scheimpflug technology (Pentacam; Oculus Optikgeräte GmbH).
J Refract Surg
September 2025
From the Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy.
Purpose: To determine the accuracy of a new machine learning-based open-source IOL formula (PEARLS-DGS) in 100 patients who underwent uncomplicated cataract surgery and had a history of laser refractive surgery for myopic defects.
Methods: The setting for this retrospective study was HUMANITAS Research Hospital, Milan, Italy. Data from 100 patients with a history of photorefractive keratectomy or laser in situ keratomileusis were retrospectively analyzed to assess the accuracy of the formula.
J Refract Surg
September 2025
From Qvision, Department of Ophthalmology of VITHAS Almería Hospital, Almería, Spain.
Purpose: To assess differences in intraocular lens (IOL) power calculation prediction error (PE) considering the manufacturing tolerance or exact power (EP) versus labeled power (LP), and to compare accuracy using the Barrett formula with optimized constant versus a thick-lens formula.
Methods: The PE and absolute PE were calculated for a random eye of patients implanted with the multifocal Liberty Q-Flex 640PM IOL (Medicontur Ltd) considering the LP and the EP provided by the manufacturer. The outcomes for the Barrett with optimized constant formula and a thick-lens formula personalized for the surgeon, biometer, and IOL were compared.
Eye (Lond)
September 2025
Department of Ophthalmology, Shanghai Key Laboratory of Visual Impairment and Restoration, Eye and ENT Hospital, Fudan University, Shanghai, China.
Objectives: To compare the accuracy of two different corneal refractive power measurements in intraocular lens (IOL) power calculation in post-myopic-LASIK eyes.
Methods: Post-myopic-LASIK patients scheduled for cataract surgery were enrolled. Corneal refractive power centred on corneal apex (K) and pupil centre (K), decentration of ablation zone, and Kappa angle were measured by Pentacam.