98%
921
2 minutes
20
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1253/circj.CJ-25-0480 | DOI Listing |
Radiology
September 2025
Department of Biomedical Informatics, Harvard Medical School, 10 Shattuck St, Boston, MA 02115.
Despite the rapid growth of Food and Drug Administration-cleared artificial intelligence (AI)- and machine learning-enabled medical devices for use in radiology, current tools remain limited in scope, often focusing on narrow tasks and lacking the ability to comprehensively assist radiologists. These narrow AI solutions face limitations in financial sustainability, operational efficiency, and clinical utility, hindering widespread adoption and constraining their long-term value in radiology practice. Recent advances in generative and multimodal AI have expanded the scope of image interpretation, prompting discussions on the development of generalist medical AI.
View Article and Find Full Text PDFStat Med
September 2025
Novartis Pharma AG, Basel, Switzerland.
One important property of any drug product is its stability over time. A key objective in drug stability studies is to estimate the shelf-life of a drug, involving a suitable definition of the true shelf-life and the construction of an appropriate estimate of the true shelf-life. Simultaneous confidence bands (SCBs) for percentiles in linear regression are valuable tools for determining the shelf-life in drug stability studies.
View Article and Find Full Text PDFSex Transm Infect
September 2025
Department of Clinical Sciences, Institute of Tropical Medicine, Antwerp, Belgium
Objectives: Describe the clinical evolution of a person with recurrent gonococcal cervicitis despite appropriate treatment and lack of reinfection.
Methods: We used the tolerance detection test to confirm that all three culture-positive gonococcal isolates were tolerant to ceftriaxone.
Results: Over a period of 6 months, a transgender man with gonococcal cervicitis experienced eight episodes of treatment failure despite receiving ceftriaxone 1 g intramuscularly on each occasion.
J Am Chem Soc
September 2025
Beijing National Laboratory for Molecular Sciences, CAS Laboratory of Colloid and Interface and Thermodynamics, Center for Carbon Neutral Chemistry, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China.
CO electroreduction to produce fuels and chemicals is of great significance. Molecular catalysts offer valuable advantages in light of their well-defined active sites and tunable structural and electronic properties. However, their stability is often compromised by rigid conjugated structures.
View Article and Find Full Text PDFJ Nephrol
September 2025
Nephrology and Dialysis Unit, ASL Nord Ovest Toscana, Livorno, Italy.
Hypertension is a clinical condition associated with an increase in cardiovascular morbidity and mortality. In chronic kidney disease (CKD), hypertension is also a driver of faster disease progression. Correct and appropriate treatment with antihypertensive medication reduces the risk of cardiovascular events and slows kidney disease progression.
View Article and Find Full Text PDF