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Study DesignRetrospective study.ObjectiveThis study aims to identify how CT HU values vary in degenerative lumbar scoliosis (DLS) patients with different scoliotic apexes and in those with different degree of scoliosis.MethodsWe included 222 DLS patients and 140 lumbar spinal stenosis (LSS) patients, dividing the DLS patients into 2 groups based on scoliotic apex location. Patients were further categorized by T scores into osteoporotic and non-osteoporotic groups, and by Cobb angle into mild (<20°) and severe (>20°) scoliosis. We analyzed CT value distribution in these groups and compared the area under the curve (AUC) for predicting osteoporosis based on HU values from different vertebrae.ResultsCT HU values for L1 and L2 were significantly lower in the DLS group compared to LSS group ( < 0.05). The lowest HU values in patients with a scoliotic apex at L2 or L2-3 were observed at the scoliotic apex region, while those with the scoliotic apex at L3, L3-4, and L4 had the lowest values at L3. This pattern was more pronounced in patients with a Cobb angle >20°. In the mild scoliosis group, the lowest CT value was found at L3 when the scoliotic apex was between L2 and L4. Additionally, L4 CT HU thresholds were better at distinguishing osteoporosis than other levels ( < 0.05), swhen the scoliotic apex was located at L2 or L2-3.ConclusionsCT HU values in DLS patients, particularly with a Cobb angle >20°, decrease at the scoliotic apex. Caution is required when using HU values from L1, L2, and L3 to assess osteoporosis in patients with a scoliotic apex at L2 and L2-3.
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http://dx.doi.org/10.1177/21925682251362138 | DOI Listing |
Global Spine J
August 2025
Orthopaedic Department, Peking University Third Hospital, Beijing, China.
Study DesignRetrospective study.ObjectiveThis study aims to identify how CT HU values vary in degenerative lumbar scoliosis (DLS) patients with different scoliotic apexes and in those with different degree of scoliosis.MethodsWe included 222 DLS patients and 140 lumbar spinal stenosis (LSS) patients, dividing the DLS patients into 2 groups based on scoliotic apex location.
View Article and Find Full Text PDFJ Pediatr Orthop
August 2025
Department of Orthopaedic Surgery, The Johns Hopkins University, Baltimore, MD.
Background: Understanding vertebral anatomy is crucial for the secure fixation of spinal instrumentation. Using MRI and CT scans can identify safe locations for pedicle screw insertion and/or discover underlying pathologies such as dural ectasia. In this study, we explored Marfan vertebrae morphology and compared it to that of idiopathic scoliotic vertebrae.
View Article and Find Full Text PDFArthritis Res Ther
March 2025
Shriners Hospital for Children, Montreal, QC, Canada.
Background: Facet joint osteoarthritis (OA) is prevalent in patients with adolescent idiopathic scoliosis (AIS). The most pronounced OA presents above and below the curve's apex where the intervertebral rotation is the greatest. This indicates that facet joint OA is implicated and potentially contributes to AIS progression.
View Article and Find Full Text PDFSci Rep
January 2025
Tuina department, Hangzhou Hospital of Traditional Chinese Medicine Hangzhou TCM Affiliated to Zhejiang Chinese Medicine University, Hangzhou, China.
To determine whether relative anterior spinal overgrowth (RASO) occurs regardless of scoliosis segments and severity, and to explore the pattern of vertebral body height changes in adolescent idiopathic scoliosis (AIS). A total of 125 AIS and 179 non-scoliotic adolescents were enrolled. The anterior vertebral body height (VBHa) and posterior vertebral body height (VBHp) were measured on lateral spine radiographs, and the VBHa/VBHp ratio was calculated.
View Article and Find Full Text PDFJ Orthop Surg Res
January 2025
Biomedical Engineering Department, Universidad de los Andes, Bogotá, Colombia.