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Background: Prolonged hot weather poses a threat to mental health. However, little is known about whether patients with mental disorders have adapted to prolonged hot weather, namely a heatwave. We aimed to analyse temporal patterns in the effect of heatwaves on mental disorders and decompose the effect of heatwave components.
Methods: We analysed the impact of heatwave on mental disorder deaths in Shanghai, China between 2008-21, using a case-crossover analysis combined with a time-varying distributed lag nonlinear model. We decomposed the effect of the heatwave into two components, including the main effect from heatwave intensity and the added effect from heatwave duration. We also examined subgroup analyses by individual characteristics (gender, age, and education).
Results: We analysed a total of 9953 mental disorder deaths. Heatwaves, including the main and added effects, were associated with an increased risk of death from mental disorders, with a higher risk from the main effect. For temporal variation, the main effect of heatwaves on overall mental disorder mortality declined over time, while an opposite trend was observed for suicide and dementia. In contrast, the added effect of heatwaves on total mental disorders, suicide, and dementia increased over time, whereas a decreasing trend was observed for schizophrenia. Regarding the number of deaths attributable to heatwaves, the main and added effects together accounted for 3.5 deaths per 100 000 population in total mental disorders, with about 37% attributable to the added effect. Elderly individuals and those with lower educational attainment were more vulnerable to heatwave exposures than their counterparts.
Conclusions: This study suggests that heatwave intensity and duration are both risk factors for death from mental disorders, without obvious evidence of adaptation to heatwaves in total mental disorders, suicide, and dementia.
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http://dx.doi.org/10.7189/jogh.15.04231 | DOI Listing |
JMIR Res Protoc
September 2025
Institute of Higher Education and Research in Healthcare, Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland.
Background: In pediatric intensive care units, pain, sedation, delirium, and iatrogenic withdrawal syndrome (IWS) must be managed as interrelated conditions. Although clinical practice guidelines (CPGs) exist, new evidence needs to be incorporated, gaps in recommendations addressed, and recommendations adapted to the European context.
Objective: This protocol describes the development of the first patient- and family-informed European guideline for managing pain, sedation, delirium, and IWS by the European Society of Paediatric and Neonatal Intensive Care.
Theor Med Bioeth
September 2025
Laboratory of Applied Epistemology, DADU, University of Sassari, Palazzo del Pou Salit, Piazza Duomo 6, 07041, Alghero, Sassari, Italy.
Orthorexia nervosa is defined as an exaggerated and obsessive fixation on healthy eating. In recent years, there has been growing debate over whether orthorexia nervosa should be considered a new psychiatric disorder. This paper discusses the conceptual issues that emerge from the attempt to identify the diagnostic criteria for orthorexia nervosa as opposed to non-pathological cases of healthy eating or 'healthy orthorexia'.
View Article and Find Full Text PDFClin Auton Res
September 2025
Faculty of Medicine, Department of Medicine, Ageing and Age-Associated Disorders Research Group, Division of Geriatric Medicine, University of Malaya, 50603, Kuala Lumpur, Malaysia.
Background: Orthostatic hypotension (OH) is prevalent in older adults and is often associated with falls. However, the presence or absence of symptoms in OH may be mediated by cerebral autoregulation, which helps maintain cerebral perfusion during blood pressure fluctuations.
Methods: We recruited 40 older adults (aged ≥ 55 years) from the Malaysian Elders Longitudinal Research (MELoR) cohort.
Eur J Neurol
September 2025
Neuroimaging Research Unit, Division of Neuroscience, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Background: Frontotemporal dementia (FTD) encompasses diverse clinical phenotypes, primarily characterized by behavioral and/or language dysfunction. A newly characterized variant, semantic behavioral variant FTD (sbvFTD), exhibits predominant right temporal atrophy with features bridging behavioral variant FTD (bvFTD) and semantic variant primary progressive aphasia (svPPA). This study investigates the longitudinal structural MRI correlates of these FTD variants, focusing on cortical and subcortical structural damage to aid differential diagnosis and prognosis.
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