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Objective: The purpose of this study was to explore the optimal needle-tip depth through conventional percutaneous vertebroplasty (PVP) and further analyze the correlation between needle-tip depth and anterior cement leakage in osteoporotic vertebral compression fractures.
Methods: A total of 560 patients with PVP were retrospectively analyzed, and they were stratified into a shallow (needle-tip at 2/3-3/4 depth, n = 291) and deep placement group (3/4-7/8 depth, n = 269). The clinical outcomes and anterior leakage rates were compared. Biomechanical parameters, including symmetric cement diffusion, flow velocity, anterior wall arrival time, and contact pressure, were derived from finite element analysis.
Results: Anterior leakage risk was significantly higher with deep placement (P = 0.005). Finite element analysis demonstrated increased distal diffusion asymmetry fraction, decreased anterior wall arrival time, increased cement flow velocity, and increased contact pressure for the deep insertion (all P < 0.0001). Risk of leakage was particularly elevated in the type 4 German Society for Orthopaedics and Trauma Surgery Osteoporotic Fracture Classification fracture group when placed deep (72.92% vs. 29.17%, P < 0.001).
Conclusions: Greater amount of cement septum extension during PVP increases anterior cement leakage risk, especially in osteoporotic fracture type 4 fractures, suggestive that practitioners should be cautious about controlling needle-depth in order to effectively minimize complications.
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http://dx.doi.org/10.1016/j.wneu.2025.124329 | DOI Listing |
J Intensive Care Med
August 2025
Institute of Critical Care Medicine, Icahn School of Medicine Mount Sinai, New York, NY, USA.
BackgroundCentral line placement is a very common inpatient procedure and the internal jugular (IJ) vein is the most commonly accessed site. Complications associated with this procedure include pneumothorax, hemothorax and pain which may be caused by accidental visceral injury with needle over-penetration.Research QuestionExtrapolating approximate needle length required to access sonographic mid-point of the internal jugular (IJ) vein.
View Article and Find Full Text PDFWorld Neurosurg
July 2025
Department of Orthopedics, Third Affiliated Hospital of Nanjing Medical University, Changzhou Second People's Hospital, Changzhou City, Jiangsu Province, China. Electronic address:
Objective: The purpose of this study was to explore the optimal needle-tip depth through conventional percutaneous vertebroplasty (PVP) and further analyze the correlation between needle-tip depth and anterior cement leakage in osteoporotic vertebral compression fractures.
Methods: A total of 560 patients with PVP were retrospectively analyzed, and they were stratified into a shallow (needle-tip at 2/3-3/4 depth, n = 291) and deep placement group (3/4-7/8 depth, n = 269). The clinical outcomes and anterior leakage rates were compared.
Sensors (Basel)
June 2025
Clinic of Nuclear Medicine, Jena University Hospital, Am Klinikum 1, 07747 Jena, Germany.
It has been demonstrated that needle guidance systems can enhance the precision and safety of ultrasound-guided punctures in human medicine. Systems that permit the utilization of commercially available standard needles, instead of those that necessitate the acquisition of costly, proprietary needles, are of particular interest. The objective of this phantom study is to evaluate the reliability and accuracy of magnet-based ultrasound needle guidance systems, which superimpose the position of the needle tip and a predictive trajectory line on the live ultrasound image.
View Article and Find Full Text PDFComput Biol Med
July 2025
Biosensor Group, KIST Europe Forschungsgesellschaft mbH, 66123, Saarbrücken, Germany; Division of Energy & Environment Technology, University of Science & Technology, 34113, Daejeon, Republic of Korea. Electronic address:
Drug delivery through the skin using miniaturised needles is a promising microtechnology-based strategy for precise control of drug release dynamics. Active injection of therapeutic insulin through hollow microneedles has recently been implemented as patch-type microsystems in which liquid dispensers and drug reservoirs are integrated with the microneedle array. Nevertheless, little is known about the relationship of the micro-infusion parameters, such as the microfluid flow rate, geometry and opening size of hollow microneedle, and needle insertion depth, to the biomechanics of viable skin multilayers and its associated pain perception, and to insulin absorption kinetics by microcirculation.
View Article and Find Full Text PDFInt J Comput Assist Radiol Surg
July 2025
Robarts Research Institute, Western University, 100 Perth St., London, ON, N6A 5B7, Canada.
Purpose: In conventional fluoroscopy-guided interventions, the 2D projective nature of X-ray imaging limits depth perception and leads to prolonged radiation exposure. Virtual fluoroscopy, combined with spatially tracked surgical instruments, is a promising strategy to mitigate these limitations. While magnetic tracking shows unique advantages, particularly in tracking flexible instruments, it remains under-explored due to interference from ferromagnetic materials in the C-arm room.
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