Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Avocados are sources of Monounsaturated fatty acids (MUFA), vitamins, minerals, fiber, phytosterols, and polyphenols. However, their effects on the lipid profiles remain unclear. This meta-analysis assessed the effect of avocado consumption on lipid levels in adults. A systematic search of PubMed, Web of Science, Scopus, and Google Scholar (up to May 24, 2024) included only randomized controlled trials. Two independent investigators screened and extracted the data. Results showed a significant reduction in total cholesterol (TC) (weighted mean difference (WMD): -6.97 mg/dL, 95% CI: -8.29, -5.65) and low-density lipoprotein Cholesterol (LDL-C) ((WMD): -6.16 mg/dL, 95% CI: -9.87, -2.44) in avocado groups vs. controls. A nonlinear dose-response analysis found an inverse association between higher avocado intake (>250 g/day) and LDL-C levels as well as between longer consumption (>23 weeks) and TC reduction. Similarly, a dose of 140-235 g/day for 4.8-9 weeks showed a significant association with triglyceride (TG) levels. Avocado consumption had no significant effect on high-density lipoprotein Cholesterol (HDL-C triglyceride (TG) levels. Further studies are required to confirm its role in the regulation of lipid profiles.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1080/10408398.2025.2531222 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Age characterization of donor based on fatty acid substances analysis in fingermarks.
Sci Justice
September 2025
Department of Forensic Science, People's Public Security University of China, Beijing 100038, China. Electronic address:
As a critical frontier in forensic science, the profiling of physical evidence characteristics has garnered substantial attention. This study employed gas chromatography-mass spectrometry (GC-MS) to investigate age-related differences in sebaceous fingermark fatty acid compositions. Fingermark samples from 80 volunteers were analyzed to characterize fatty acid profiles across different age groups.
View Article and Find Full Text PDFAssociation of METS-IR with Pregnancy Outcomes in Euthyroid Women: A Retrospective Cohort Study.
Horm Metab Res
September 2025
Department of Obstetrics, Fujian Maternity and Child Health Hospital, Fuzhou, China.
The non-insulin-based metabolic score for insulin resistance (METS-IR) is a recently developed index aimed at being a practical and efficient alternative biomarker of insulin resistance (IR). This study aimed to investigate the association between METS-IR in euthyroid women in the first trimester of pregnancy and pregnancy outcomes. A total of 1810 participants who gave birth at Fujian Maternity and Child Health Hospital from November 2018 to November 2019 were included in this study.
View Article and Find Full Text PDFHydrodynamic focusing to synthesize lipid-based nanoparticles: Computational and experimental analysis of chip design and formulation parameters.
J Control Release
September 2025
Institute of Biomedical Engineering, University of Toronto, Toronto, Ontario M5S 3G9, Canada; The Keenan Research Centre for Biomedical Science of St. Michael's Hospital, Unity Health Toronto, Toronto, Ontario M5B 1T8, Canada; Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Ontario M
Microfluidic hydrodynamic focusing (HF) has emerged as a powerful platform for the controlled synthesis of lipid nanoparticles (LNPs) and liposomes, offering superior precision, reproducibility, and scalability compared to traditional batch methods. However, the impact of HF inlet configuration and channel geometry on nanoparticle formation remains poorly understood. In this study, we present a comprehensive experimental and computational analysis comparing 2-inlet (2-way) and 4-inlet (4-way) HF designs across various sheath inlet angles (45°, 90°, 135°) and cross-sectional geometries (square vs.
View Article and Find Full Text PDFIndividual and collaborative solid-state fermentation by Monascus purpureus and Eurotium cristatum: Impact on metabolite profiling and hypolipidemic properties of black Tartary buckwheat.
Food Chem
September 2025
College of Biomass Science and Engineering and Healthy Food Evaluation Research Center, Sichuan University, Chengdu 610065, China.
The growing demand for healthy Tartary buckwheat-based foods has sparked interest in fermentation as a processing technique to enhance food quality and bioactivity. This study investigated the impact of solid-state fermentation of black Tartary buckwheat (BTB) with Monascus purpureus and Eurotium cristatum PW-1 on its quality, biochemical properties, and hypolipidemic potential, using metabolomics, bioinformatics, network pharmacology, and invivo zebrafish models. Fermentation significantly increased total amino acids, γ-aminobutyric acid, and aromatic volatile compounds such as alcohols, esters, terpenes, and terpenoids, enhancing the flavor profile.
View Article and Find Full Text PDFEffects of prolonged unsaturated fatty acid supplementation on reproductive competence and metabolic profiles in serum and follicular fluid of Holstein heifers.
Anim Reprod Sci
September 2025
Department of Animal Production and Animal Nutrition, University of Sao Paulo, Pirassununga 13635-900, Brazil. Electronic address:
This study evaluated the effects of a 120-d dietary supplementation with unsaturated fatty acids from soybean grain and flaxseed on oocyte quality, in vitro embryo quality and production, and the metabolic profiles of blood and follicular fluid in Holstein heifers. Twenty-four heifers were assigned to the following treatments: a control diet (CON) and diets supplemented with whole raw soybeans (WRS) or flaxseed (FLX), both formulated to increase ether extract content to approximately 4.5 % dry matter (DM).
View Article and Find Full Text PDF