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Article Abstract
The ( ) mutation first described by Morgan and Bridges in 1915 has adult visible phenotypes in wing posture and vein formation. We have mapped to a genomic region within the ( ) gene that houses the cis-regulatory elements that control expression of the Iroquois Complex genes ( ) and ( ) in the wing hinge and wing veins. Sequence analysis of the allele has identified a gtwin retrotransposon containing su(Hw) insulator binding sites within this region of . We find that mutations in suppress the phenotype, providing a potential mechanism for the insertion to affect the function of the Iroquois Complex.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12311624 | PMC |
| http://dx.doi.org/10.17912/micropub.biology.001704 | DOI Listing |
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