Category Ranking

98%

Total Visits

921

Avg Visit Duration

2 minutes

Citations

20

Article Abstract

Optic neuropathy due to vascular compression is a rare and poorly understood phenomenon. While contact between the optic nerve and nearby arteries is not uncommon, in most cases, it is an incidental finding in asymptomatic patients. Vascular compression has previously been suggested to be associated with optic neuropathy and visual dysfunction, with a plausible role for surgical decompression in appropriately selected patients. We present the case of a 63-year-old male who presented with eight years of progressive left optic neuropathy with worsening binocular diplopia, visual field deficits, depth perception, and color vision. Left-sided fundus exam demonstrated diffuse pallor. Imaging demonstrated atrophy of the left optic nerve with compression by the A1 segment of the anterior cerebral artery. Extensive neuro-ophthalmology workup did not reveal other conceivable causes for his presentation. The patient underwent a left supraorbital craniotomy for microvascular decompression through an eyebrow incision, during which the left A1 was found to be compressing the left optic nerve. The artery was released and the nerve decompressed using felt pledgets. Postoperatively, the patient experienced subjective and objective improvement in visual acuity. Our case suggests that patients with progressive optic neuropathy, radiographic evidence of vascular compression, and no alternative cause for visual dysfunction should be carefully evaluated for consideration of microvascular decompression.

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.clineuro.2025.109062DOI Listing

Publication Analysis

Top Keywords

optic nerve
16
optic neuropathy
16
microvascular decompression
12
vascular compression
12
left optic
12
supraorbital craniotomy
8
craniotomy microvascular
8
optic
8
anterior cerebral
8
cerebral artery
8

Similar Publications

Introduction: The definition of Leber's hereditary optic neuropathy (LHON) does not take into account a preclinical phase during which the thickness of retinal nerve fiber layer (RNFL) is increased, prior to optic nerve atrophy, reducing the chances of visual recovery.

Objectives: Search for a metabolomic signature characterizing this preclinical phase and identify biomarkers predicting the risk of LHON onset.

Methods And Results: The blood and tear metabolomic profiles of 90 asymptomatic LHON mutation carriers followed for one year will be explored as a function of RNFL thickness and compared to those of a healthy control.

View Article and Find Full Text PDF

Deep Learning Estimation of 24-2 Visual Field Map from Optic Nerve Head Optical Coherence Tomography Angiography.

J Glaucoma

September 2025

Hamilton Glaucoma Center, Shiley Eye Institute, Viterbi Family Department of Ophthalmology, University of California San Diego, La Jolla, CA, United States.

Precis: Artificial intelligence applied to OCTA images demonstrated high accuracy in estimating 24-2 visual field maps by leveraging information from pararpapillary area.

Purpose: To develop deep learning (DL) models estimating 24-2 visual field (VF) maps from optical coherence tomography angiography (OCTA) optic nerve head (ONH) en face images.

Methods: A total of 3148 VF OCTA pairs were collected from 994 participants (1684 eyes).

View Article and Find Full Text PDF

3D Structural Phenotype of the Optic Nerve Head in Glaucoma and Myopia - A Key to Improving Glaucoma Diagnosis in Myopic Populations.

Am J Ophthalmol

September 2025

Singapore Eye Research Institute, Singapore National Eye Centre, Singapore; Duke-NUS Graduate Medical School, Singapore; Department of Ophthalmology, Emory University School of Medicine, Emory University; Department of Biomedical Engineering, Georgia Institute of Technology/Emory University, Atlanta

Purpose: To characterize the 3D structural phenotypes of the optic nerve head (ONH) in patients with glaucoma, high myopia, and concurrent high myopia and glaucoma, and to evaluate their variations across these conditions.

Design: Retrospective cross-sectional study.

Participants: A total of 685 optical coherence tomography (OCT) scans from 754 subjects of Singapore-Chinese ethnicity, including 256 healthy (H), 94 highly myopic (HM), 227 glaucomatous (G), and 108 highly myopic with glaucoma (HMG) cases METHODS: We segmented the retinal and connective tissue layers from OCT volumes and their boundary edges were converted into 3D point clouds.

View Article and Find Full Text PDF

Purpose: To compare retinal ganglion cell (RGC) loss in glaucoma suspect eyes with diffuse versus localized neuroretinal rim loss at the time of the first confirmed visual field defect.

Design: Prospective observational cohort study.

Subjects: Fifty-three glaucoma suspect eyes and 124 healthy eyes.

View Article and Find Full Text PDF

Primary open-angle glaucoma (POAG) is characterized by chronic progressive damage to the retinal ganglion cell layer (GCL) and their axons, leading to gradual visual function loss. Currently, the gold standards for structural and functional assessment of the retina in glaucoma are static automated perimetry (SAP) and optical coherence tomography (OCT). However, in clinical practice, data from SAP and OCT may be insufficient to reliably determine the stage of glaucomatous optic neuropathy, monitor its progression, or differentiate it from other causes of visual dysfunction.

View Article and Find Full Text PDF