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Background: Social participation is recognised as a significant factor influencing the functional ability of older adults globally. However, current evidence remains inconclusive to determine which interventions are the most effective and widely acceptable.
Purpose: This study aimed to compare the effectiveness and acceptability of non-pharmacological interventions in improving social participation among older adults.
Methods: A comprehensive search was performed across eight electronic literature databases from inception to 1 August 2024 for randomised controlled trials. Pairwise meta-analysis and network meta-analyses were sequentially performed for direct comparisons and network meta-analysis, respectively. The surface under the cumulative ranking curve (SUCRA) was used to calculate the intervention hierarchy.
Results: A total of 54 studies involving nine types of non-pharmacological interventions and two control conditions, and 8,769 participants were included. For effectiveness, the results of the network meta-analysis identified a positive effect of multicomponent rehabilitation intervention, health education and social interaction intervention on improving social participation compared with care-as-usual (Standardized Mean Differences [SMDs] ranged from 0.32 to 0.77). For acceptability, home environment adaption, psychological intervention and social interaction intervention was significantly less acceptable than comprehensive exercise intervention (Odds Ratios [ORs] from 3.86 to 5.28). The SUCRA ranking showed that the multicomponent rehabilitation intervention ranked highest in both effectiveness and acceptability. Most comparisons were rated as `moderate' to `low' for the certainty of evidence.
Conclusion: The multicomponent rehabilitation intervention emerged as the most effective and acceptable strategy for enhancing social participation among older adults. However, further rigorous studies are needed to solidify these findings on the potential benefits of non-pharmacological interventions.
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http://dx.doi.org/10.1093/ageing/afaf193 | DOI Listing |
Dev Med Child Neurol
September 2025
School of Health and Social Development, Faculty of Health, Deakin University, Geelong, Australia.
Aim: To understand communication about sexuality for adolescents with cerebral palsy (CP) and complex communication needs.
Method: We systematically searched primary research on adolescents aged 10 to 24 years with CP and/or complex communication needs. We coded the primary evidence against themes derived from a theoretical framework analysis.
Public Health Genomics
September 2025
Introduction Deliberative democracy is an inclusionary approach to reaching consensus decision-making through participative and representative engagement. The Democratizing Education for Sickle Cell Disease Gene Therapy Project used a deliberative community engagement model to partner with patient advocacy and research community members within the field of sickle cell disease (SCD) gene therapy to create new, accessible patient education materials (PEMs) about SCD gene therapy. Objective Develop PEMs for sickle cell disease gene therapy and study the process of deliberative community engaged research Methods A study of the experiences of a multi-disciplinary group of participants including patients, patient advocates, health professionals, gene therapy researchers, industry and government members using a deliberative community engagement model to develop new PEMs.
View Article and Find Full Text PDFAmbio
September 2025
Department of Sustainable Development, Environmental Science and Engineering (SEED), KTH Royal Institute of Technology, Stockholm, Sweden.
This study investigates how the seven core resilience principles are integrated into assessments of forest system resilience to natural or human-induced disturbances across engineering, ecological, and social-ecological resilience concepts. Following PRISMA guidelines, a literature search in the Web of Science database using the keywords "resilience", "forest" and "ecosystem services" yielded 1828 studies, of which 330 met the selection criteria. The most commonly used criterion was diversity, a sub-criterion of "diversity and redundancy", appearing in 50% of studies.
View Article and Find Full Text PDFJ Neural Transm (Vienna)
September 2025
Department of Clinical and Health Psychology, University of Vienna, Liebiggasse 5, Vienna, 1010, Austria.
Tiredness may be associated with increased or decreased sexual experience and behavior while fatigue seems to have a predominantly negative effect, although evidence is scarce. This ecological momentary assessment study is the first to examine associations between tiredness or fatigue and concurrent / subsequent sexual desire or sexual arousal and previous / subsequent sexual activity in daily life, including event-based measurements and considering gender differences. Healthy heterosexual individuals (n = 63), aged between 19 and 32 years and in a relationship, indicated their tiredness, general fatigue, physical fatigue, sexual desire, and sexual arousal on an iPod seven times daily over 14 days, and any event-based occurrences of sexual activity.
View Article and Find Full Text PDFBMJ Open
September 2025
Amsterdam University Medical Centres, Amsterdam, Netherlands
Objective: Despite global efforts, gender disparities in oncology may persist. Understanding these disparities within the context of major conferences can inform strategies to promote gender inclusiveness in the field. This study evaluates the participation of women and men at the American Society of Clinical Oncology (ASCO) 2024 congress, focusing on chairs, speakers and audience questioners.
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