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Purpose: The purpose of this study was to report the one-year posterior fusion rate in patients with adult spinal deformity (ASD) undergoing posterior spinal fusion (PSF) with supplemental lumbar interbody fusion (LIF).
Methods: Patients with ASD who underwent PSF with supplemental ALIF and/or XLIF between October 2021 and December 2023 were prospectively enrolled. Fusion was assessed using fine-cut CT scans with Metal Artifact Reduction (MAR) and multi-planar reconstruction (MPR) one year after surgery, and each level was graded for interbody and posterolateral fusion (Glassman Classification). Interbody and posterolateral fusion were reported as individual fusion grades (1-4) and dichotomized as; Fusion (1-2) and non-fusion (3-4).
Results: Of 57 enrolled patients, 50 had CT scans performed with 53 ALIF and 48 XLIF-treated levels. The mean age was 63.5 ± 11.6 years and 36 (72%) were female. Solid fusion of the interbody and/or posterolateral fusion assessed at the level of the LIF was obtained in 48 (96%) of the patients. Solid interbody fusion was significantly more frequent with ALIF; 49 (93%) compared to XLIF; 26 (54%) (p < 0.001). Additionally, the fusion score was significantly different with ALIF; median 1 [IQR 1-1] compared to XLIF median 2 [IQR 1-3] (p < 0.001). The posterolateral fusion rates did not differ significantly between ALIF (92%) and XLIF (88%) levels/segments (p = 0.470). Additionally, median Glassman scores for posterolateral fusion were similar: ALIF 1 [1, 1] vs. XLIF 1 [1, 2] (p = 0.370). Mechanical failure was observed in 9 patients (Displacement of the cage: 3, sacral screw loosening: 3, screw loosening: 1, rod breakage: 2) four of which were at the level of the LIF. Three patients underwent revision surgery at the level of the LIF.
Conclusion: Patients undergoing posterior instrumented fusion for ASD with supplemental anterior interbody fusion obtained high fusion rates assessed with CT. Higher rates of interbody fusion were observed in ALIF than in XLIF-treated levels. Despite differences in interbody fusion, similar posterolateral fusion was seen one year after surgery.
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http://dx.doi.org/10.1007/s00586-025-09150-y | DOI Listing |
J Pain Palliat Care Pharmacother
September 2025
Spine Unit, Orthopaedic Surgery and Traumatology Department, Catholic University and Polytechnic Hospital, Valencia, Spain.
Dexmedetomidine (DEX) has been proposed as an opioid-sparing adjunct after spinal fusion, but its efficacy across age groups is unclear. We conducted a systematic review and meta-analysis following PRISMA and registered in International Prospective Register of Systematic Reviews (PROSPERO) (CRD42024531252). Twelve studies (RCTs and cohorts; n=1,644) were included.
View Article and Find Full Text PDFClin Transl Med
September 2025
Shanghai Institute of Infectious Disease and Biosecurity, Key Laboratory of Medical Molecular Virology (MOE/NHC/CAMS), School of Basic Medical Sciences, Institute of Biomedical Sciences, Fudan University, Shanghai, China.
Leuk Lymphoma
September 2025
Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Nan Fang Yi Ke Da Xue Xue Bao
August 2025
School of Biomedical Engineering, Southern Medical University, Guangzhou 510515, China.
Objectives: We propose a myocardial infarction (MI) detection and localization model for improving the diagnostic accuracy for MI to provide assistance to clinical decision-making.
Methods: The proposed model was constructed based on multi-scale field residual blocks fusion modified channel attention (MSF-RB-MCA). The model utilizes lead II electrocardiogram (ECG) signals to detect and localize MI, and extracts different levels of feature information through the multi-scale field residual block.
Croat Med J
August 2025
Damjan Dimnjaković, Zagreb University Hospital Center, Department of Orthopaedic Surgery, Šalata 7, 10000 Zagreb, Croatia,
Aim: To assess the optimal fusion angle of the elbow to accommodate the activities of daily living.
Methods: The study enrolled 30 healthy adult volunteers (mean age 24 years), who performed 29 activities with an elbow brace fixed at various flexion angles (30°, 50°, 70°, 90°, 110°, 120°). The activities were divided into three groups: the activities of daily living, personal care and hygiene, and modern activities of daily living.