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Purpose: Shepherd's crook deformity is a characteristic complication of fibrous dysplasia (FD) of the femur, leading to coxa vara and mechanical instability. Two-stage surgical approaches involve initial valgus osteotomy followed by delayed intramedullary femoral stabilization, prolonged treatment, and increasing morbidity. This study evaluates a one-stage surgical correction that employs fibular strut allograft augmentation for both the femoral neck and shaft.
Methods: A retrospective review was performed on 17 patients with Shepherd's crook deformity who underwent one-stage hip lag screw and side plate fixation with fibular strut allograft augmentation of the femoral neck and shaft between 2002 and 2022. Radiographic and clinical outcomes were assessed, including neck-shaft angle (NSA) restoration, fixation stability, graft incorporation, and functional improvement. The median follow-up of the patients was 96 months.
Results: The mean preoperative NSA was 93° (SD: 13.5°), improving significantly to 130° (SD: 5°) at the latest follow-up (p < 0.001). Stable fixation was achieved in 16 of 17 patients, with one case of fixation failure. Fibular graft resorption was noted in six patients but did not compromise fixation. Clinically, postoperative pain, limping, and activity limitations improved substantially, though seven patients experienced persistent restrictions in outdoor activities. The average limb shortening was 3.5 cm before the operation and 0.9 cm at the end of the follow-up.
Conclusion: One-stage correction of Shepherd's crook deformity using lag hip screw fixation and fibular strut allograft augmentation could be a viable alternative to staged procedures, though further studies are needed to confirm its efficacy and generalizability.
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http://dx.doi.org/10.1007/s00264-025-06627-9 | DOI Listing |
Background: Sotrovimab is a neutralising monoclonal antibody targeting the SARS-CoV-2 spike protein. We aimed to evaluate the efficacy and safety of sotrovimab in the RECOVERY trial, an investigator-initiated, individually randomised, controlled, open-label, adaptive platform trial testing treatments for patients admitted to hospital with COVID-19.
Methods: Patients admitted with COVID-19 pneumonia to 107 UK hospitals were randomly assigned (1:1) to either usual care alone or usual care plus a single 1 g infusion of sotrovimab, using web-based unstratified randomisation.
J Plast Reconstr Aesthet Surg
August 2025
Division of Plastic Surgery, Department of Surgery, Mayo Clinic, 200 1st St SW, Rochester 55905, MN, USA; Department of Pediatric and Adolescent Medicine, Mayo Clinic, 200 1st St SW, Rochester 55905, MN, USA. Electronic address:
McCune-Albright syndrome (MAS) is defined by a triad of fibrous dysplasia (FD), hyperfunctioning endocrinopathies, and café-au-lait spots. FD, characterized by the fibrous replacement of healthy bone, is a major source of morbidity in MAS. To characterize skeletal involvement and associated endocrinopathies in patients with MAS/FD, we conducted a retrospective review of patients with the diagnosis of both MAS and FD treated at our center between 1989 and 2024.
View Article and Find Full Text PDFInt Orthop
September 2025
Bone and Joint Reconstruction Research Center, Department of Orthopedics, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Purpose: Shepherd's crook deformity is a characteristic complication of fibrous dysplasia (FD) of the femur, leading to coxa vara and mechanical instability. Two-stage surgical approaches involve initial valgus osteotomy followed by delayed intramedullary femoral stabilization, prolonged treatment, and increasing morbidity. This study evaluates a one-stage surgical correction that employs fibular strut allograft augmentation for both the femoral neck and shaft.
View Article and Find Full Text PDFFront Surg
June 2025
Department of Orthopedics, Affiliated Zhongshan Hospital of Dalian University, Dalian, China.
Background: Osteofibrous dysplasia is a congenital, non-hereditary benign bone disease characterized by localized bone protrusion and replacement of normal bone cancellous by proliferating abnormal bone fibers. For this case, there is no unified treatment standard for internal fixation reconstruction or replacement, which is mainly based on comprehensive evaluation of each patient's clinical history and imaging findings.
Case Presentation: We report a case of systemic multiple osteofibrous dysplasia complicated by left femoral bone fracture, left proximal-femur shepherd's crook deformity, and femoral pseudojoint formation.
J Am Acad Orthop Surg
June 2025
From the Department of Orthopedics, Medstar Georgetown University Hospital (Johnson and Jacquez), the Georgetown University School of Medicine (Anderson), and Department of Orthopedics, Medstar Georgetown University Hospital (Adams).
Fibrous dysplasia is a benign condition that is characterized by the inability of bone-forming tissue to produce mature lamellar bone, creating a radiolucent lesion of immature bone within the medullary canal of the affected bone. Typically occurring in the long bones, this process can lead to pathologic fractures, debilitating pain, and malignant transformation and may be associated with Mazabraud syndrome, severe polyostotic disease, and McCune-Albright syndrome. Fibrous dysplasia can be treated most effectively if caught early with nonsurgical diphosphonate therapy, which has been shown to improve cortical thickness and reduce pathologic fractures.
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