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is the leading bacterial cause of gastroenteritis associated with aquatic food consumption globally. This study aimed to determine the prevalence of in aquatic foods from Huzhou and to identify the serotypes, antimicrobial resistance, virulence factors, and genetic relatedness of the strains. A total of 306 isolates were detected from 1314 aquatic food samples from 2022 to 2024. The results indicated that the most prevalent serotypes were O1:KUT (17.0%), O2:K28 (13.7%), and O2:KUT (13.1%). Multilocus sequence typing analysis divided the 306 isolates into 175 sequence types (STs), and the predominant sequence type was ST864 (3.3%). Antimicrobial susceptibility tests showed that 2.6% of isolates were multidrug resistant. High resistance was observed to ampicillin (64.7%) and streptomycin (44.4%). A total of seven antimicrobial categories of resistance genes were identified, and the resistance gene was detected in all isolates. The virulence genes and were found in 16 (5.2%) and 12 (3.9%) isolates, respectively. In addition, we observed that all the 306 isolates encode type III secretion systems 1. The phylogenomic analysis based on the whole-genome sequence revealed that the 306 isolates were divided into four clusters. Our findings broaden perspectives on genetic diversity and enhance our ability to assess the potential risks of its spread.
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http://dx.doi.org/10.3390/foods14142481 | DOI Listing |
Infect Drug Resist
August 2025
Department of Molecular Epidemiology of Bacterial Infections, Institute for Hygiene and Microbiology, University of Würzburg, Sanderring 2, Würzburg, 97070, Germany.
Background And Purpose: Bloodstream infections (BSIs) caused by antimicrobial-resistant pathogens, especially WHO-Bacterial-Priority-Pathogens (WHO-BPPs), contribute to significant mortality. The current study determined the prevalence of BSIs, causative bacterial pathogens and their antimicrobial susceptibility profiles, and factors associated with laboratory-confirmed BSIs by WHO-BPPs during and after National Action Plan on Antimicrobial Resistance (NAP-AMR) implementation in Mwanza, Tanzania.
Patients And Methods: A comparative cross-sectional study was conducted among sepsis patients in District, Regional, and Zonal Referral Hospitals from June 2019 to June 2020 (during NAP-AMR) and March to July 2023 (after NAP-AMR).
Neurosurgery
July 2025
Department of Neurosurgery, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Background And Objectives: Major depressive disorder affects approximately 10% of all adults in the United States, but the condition remains underdiagnosed for patients with degenerative spine disease and radicular pain. The impact of comorbid undiagnosed depression on postoperative outcomes after lumbar fusion is not well characterized and may contribute to excessive health care utilization. This study isolates the relationship between undiagnosed depression, assessed by the Patient Health Questionnaire 2 (PHQ-2) screening tool, and short-term postoperative outcomes after single-level posterior lumbar fusion.
View Article and Find Full Text PDFOrphanet J Rare Dis
September 2025
Université Côte d'Azur, Service Système Nerveux Périphérique & Muscle, Centre Hospitalier Universitaire de Nice, Nice, France.
Background: Facioscapulohumeral muscular dystrophy (FSHD) is characterized by a typical pattern of muscle involvement, yet it encompasses a wide spectrum of phenotypes, including less common features that remain incompletely defined in the literature. While previous studies have highlighted this clinical variability, no consensus has been reached on how to classify uncommon manifestations, nor have specific predictors been identified. This study aims to describe these uncommon features and explore potential predictors, utilizing data from the French FSHD registry.
View Article and Find Full Text PDFNPJ Precis Oncol
August 2025
Radboud University Medical Center, Medical BioSciences, Nijmegen, The Netherlands.
Around 20% of patients with primary high-grade ovarian cancer do not respond to chemotherapy, but predictive biomarkers are lacking. The purpose of the current study is to establish and clinically validate an ex vivo 3D micro-tumour testing platform that predicts patient-specific response to standard of care chemotherapy. 104 ovarian cancer patients with malignant ascites were included in the study.
View Article and Find Full Text PDFMicroorganisms
August 2025
Department of Infectious Diseases and Preventive Medicine, Faculty of Veterinary Medicine, University of Life Sciences "King Mihai I" from Timişoara, 300645 Timişoara, Romania.
This cross-sectional study evaluated the seroprevalence and clinical impact of West Nile virus (WNV) infection in horses from three ecologically high-risk counties in western Romania (Timiș, Arad, and Bihor) between 2023 and 2025. A total of 306 unvaccinated horses were tested using a commercial ELISA, with 8.17% testing positive for WNV antibodies, indicating prior exposure.
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