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: Dental eruption pathways could be influenced by several factors, both general and local, with different prevalence and morbidity. This study aims to report our experience of pediatric impacted teeth due to local factors, with the exclusion of the third molars, illustrating their prevalence, diagnostic and therapeutic pathways, and treatment outcomes. : The inclusion criteria were minor age (<18 years) and the presence of impacted teeth due to a local cause, excluding wisdom teeth. The complete diagnostic and therapeutic procedures and their outcomes were described. The relationship between the treatment and the outcomes was assessed with a chi-square test. : One hundred twelve patients with a single impaction were included in the study. The local causes of single impaction were: 63 odontogenic cysts (57%), 24 supernumerary teeth (21%), 17 odontogenic tumors (15%), and eight primary bone lesions (7%). During the follow-up period, 83 teeth erupted spontaneously 12-36 months following surgery (74%), 12 were extracted during surgery (11%), and 17 needed orthodontic traction to achieve their aesthetic and functional position (15%). The relationship between mini-invasive surgery and spontaneous eruption was significant ( < 0.00001). : Within the limitations of this study, mini-invasive surgical treatment preceded by a correct diagnosis may lead to a spontaneous eruption of permanent teeth, avoiding further orthodontic intervention and premature loss of permanent teeth.
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http://dx.doi.org/10.3390/children12070929 | DOI Listing |
Odontology
September 2025
Schulich School of Medicine & Dentistry, University of Western Ontario, London, ON, Canada.
This study aimed to investigate the age-related alterations in mesial roots of mandibular first molar in terms of root canal curvature values, dentin thickness, interorifice distance, deviation from apical foramen, and location of apical foramen using a three-dimensional curvature measurement method and micro-computed tomography (micro-CT). Forty-five mesial roots of mandibular first molars from three age groups (Group 1: ≤ 30 years, Group 2: 31-59 years, Group 3: ≥ 60 years) were scanned using micro-CT. The central axis of each mesiobuccal and mesiolingual canal was analyzed using cubic B-spline curves to calculate canal curvature.
View Article and Find Full Text PDFOrthod Craniofac Res
September 2025
Department of Orthodontics, College of Dentistry, University of Florida, Gainesville, Florida, USA.
Objective(s): In this pilot study, exosomes from saliva were isolated and tested for the presence of metabolomic biomarkers for physiological external root resorption and/or pathological alveolar bone resorption.
Settings And Sample Population: Saliva samples of 20 individuals in the mixed dentition stage of dental development.
Materials And Methods: Saliva was obtained from healthy control children with resorbing primary teeth or children with localised aggressive periodontitis (LAP) showing alveolar bone loss but little root resorption.
Elife
September 2025
Department of Earth and Environmental Sciences, Paleontology and Geobiology, Ludwig Maximilians-Universität München, Munich, Germany.
The rapid emergence of mineralized structures in diverse animal groups during the late Ediacaran and early Cambrian periods likely resulted from modifications of pre-adapted biomineralization genes inherited from a common ancestor. As the oldest extant phylum with mineralized structures, sponges are key to understanding animal biomineralization. Yet, the biomineralization process in sponges, particularly in forming spicules, is not well understood.
View Article and Find Full Text PDFIndian J Endocrinol Metab
August 2025
Department of Endocrinology and Metabolism, All India Institute of Medical Sciences, New Delhi, India.
Introduction: Tumour-induced osteomalacia (TIO) is rare. At our referral centre, we see a substantial number of TIO. Therefore, we planned to study their profile and treatment outcomes to provide insight in management.
View Article and Find Full Text PDFInt Endod J
September 2025
Department of Biochemistry, School of Dentistry, IHBR, Kyungpook National University, Daegu, South Korea.
Aim: Prickle planar cell polarity (PCP) protein 2 (Prickle2) encodes a homologue of Drosophila prickle and is involved in the non-canonical Wnt/PCP signalling pathway. However, its exact role in dentinogenesis remains unclear. Dentinogenesis, a key process in tooth morphogenesis, involves the patterned arrangement of odontoblasts and the formation of dentine matrix along the pulp cavity.
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