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The article proposes an innovative single-stage modular three-phase Power Factor Correction (PFC) converter featuring fewer current controllers. This technique leverages a practical DC-DC Quadratic Boost Converter (QBC) for PFC in Wind Energy Conversion Systems (WECS). An equivalent circuit with the non-ideal QBC is established and its small-signal model is derived, followed by a cascade control of inner current loops and outer voltage loops. The suggested linear quadratic regulator for linear matrix inequality-based PI control strategy ensures sinusoidal supply currents with a high power factor (PF) and low percentage Total Harmonic Distortion (THD) for line, servo, and regulatory operations, while addressing imbalances in the magnitude of the supply voltage. Additionally, the PFC method regulates the load voltage, and the minimal number of current controllers reduces computational tasks, losses, and overall cost. MATLAB/Simulink is used to simulate the suggested system, which uses the extended symmetrical components approach for reference current generation. The QBC's effectiveness is validated under diverse working conditions using a DSPIC30F2010 controller for a 300 W prototype. The results affirm the efficacy of the proposed technique, showcasing improved efficiency with fewer current controllers.
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http://dx.doi.org/10.1016/j.isatra.2025.07.012 | DOI Listing |
Mol Pharm
September 2025
Affiliated Hospital of Shandong Second Medical University, Shandong Second Medical University, Weifang 261053, Shandong, P. R. China.
Myocardial injury constitutes a life-threatening complication of sepsis, driven by synergistic oxidative-inflammatory pathology involving dysregulated production of reactive oxygen species (ROS), reactive nitrogen species (RNS), and proinflammatory cytokines. This pathophysiological cascade remarkably elevates morbidity and mortality rates in septic patients, emerging as a key contributor to poor clinical outcomes. Despite its clinical significance, no clinically validated therapeutics currently exist for managing septic cardiomyopathy.
View Article and Find Full Text PDFAm J Public Health
October 2025
Alexander Furuya, Asa Radix, Adam Whalen, Jessica Contreras, Jenesis Merriman, Krish J. Bhatt, Roberta Scheinmann, and Dustin T. Duncan are with the Department of Epidemiology, Columbia University Mailman School of Public Health, New York, NY. Yusuf Ransome is with the Department of Social and Behav
To examine how one's community connectedness may act as a source of resilience and promote HIV prevention and care behaviors among transgender women of color. We analyzed survey data from 313 transgender women of color living in New York City collected from August 2020 to November 2022. The Community Connectedness Scale asks participants about their baseline feelings of connection, feelings of inclusion, feelings of belonging, feelings of isolation, and feelings of being unlike in relation to the transgender community.
View Article and Find Full Text PDFJMIR Public Health Surveill
September 2025
Hospital Israelita Albert Einstein, 755 Comendador Elias Jafet Street, L1 Floor, Room 134, São Paulo, 05653-000, Brazil.
Background: The Brazilian project, launched in 2021, aims to establish a nationwide injury registry that systematically collects detailed information on incidents and individuals across the country, regardless of injury severity. The registry integrates information from prehospital and hospital care, various health systems lacking interoperability, and data from sectors such as firefighters and police. Its primary aim is to enhance health surveillance by providing timely, high-quality information that guides prevention strategies and informs policymaking.
View Article and Find Full Text PDFArq Bras Cardiol
September 2025
Instituto do Coração do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, SP - Brasil.
Targeted temperature management (TTM) is currently the only potentially neuroprotective intervention recommended for post-cardiac arrest care. However, there are concerns among the scientific community regarding conflicting evidence supporting this recommendation. Moreover, the bulk of trials included in systematic reviews that inform guidelines and recommendations have been conducted in developed countries, with case mix and patient characteristics that significantly differ from the reality of developing countries such as Brazil.
View Article and Find Full Text PDFSci Adv
September 2025
Key Laboratory of Soybean Disease and Pest Control (Ministry of Agriculture and Rural Affairs), Key Laboratory of Plant Immunity, College of Life Sciences, Nanjing Agricultural University, Nanjing 210095, China.
Salicylic acid (SA) is a key defense hormone shaped by temperature. High temperatures suppress, while low temperatures enhance, SA biosynthesis and signaling, thereby influencing plant immunity and temperature resilience. This review synthesizes current understanding of how temperature modulates SA pathways and their cross-talk with other hormones to balance growth and defense.
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