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The presence of excessive folds or scar tissue in the inguinal region significantly complicates the intraperitoneal suturing of the internal ring when employing a laparoscopic transumbilical approach for repairing inguinal hernias in male pediatric patients. From January 2020 to March 2024, we utilized three distinct surgical techniques-needle-to-needle suturing, auxiliary suture-assisted suturing, and additional port-assisted suturing-to address the internal ring with excessive folds or scar tissue in 112 male pediatric patients who underwent laparoscopic transumbilical intraperitoneal repair for inguinal hernias at our hospital. For each technique, we recorded the duration of unilateral internal ring suturing as well as instances of bleeding, surgical complications, length of hospital stay, and recurrence rate. All procedures were successfully completed without conversion to open surgery. There was one instance of bleeding associated with the needle-to-needle technique used for internal ring suturing; however, no other complications were observed. The duration of unilateral internal ring suturing varied as follows: 3.1 ± 0.3 min for the needle-to-needle technique (47 cases), 2.8 ± 0.2 min for the auxiliary suture-assisted technique (49 cases), and 2.2 ± 0.3 min for the additional port-assisted technique (29 cases). All patients underwent day surgery, and there was a 0% recurrence rate at six months post-operation. Distinct surgical techniques-needle-to-needle suturing, auxiliary suture-assisted suturing, and additional port-assisted suturing-hold significant clinical value for laparoscopic transumbilical intraperitoneal suturing of the internal ring in male pediatric patients. The optimal surgical approach should be customized based on the patient's anatomy and the surgeon's expertise.
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http://dx.doi.org/10.1038/s41598-025-12539-w | DOI Listing |
J Int Assoc Provid AIDS Care
September 2025
Department of Internal medicine, School of Medicine, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.
BackgroundDolutegravir (DTG)-based antiretroviral treatment is now the recommended regimen because of its high efficacy and fewer adverse effects. Nonetheless, hyperglycemia as adverse effect of DTG was reported in few clinical observations.MethodsA case-control study was carried out among DTG-based antiretroviral therapy (ART) users during the study period.
View Article and Find Full Text PDFNMR Biomed
October 2025
High-Field MR Center, Department of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, Vienna, Austria.
The human kidneys play a pivotal role in regulating blood pressure, water, and salt homeostasis, but assessment of renal function typically requires invasive methods. Deuterium metabolic imaging (DMI) is a novel, noninvasive technique for mapping tissue-specific uptake and metabolism of deuterium-labeled tracers. This study evaluates the feasibility of renal DMI at 7-Tesla (7T) to track deuterium-labeled tracers with high spatial and temporal resolution, aiming to establish a foundation for potential clinical applications in the noninvasive investigation of renal physiology and pathophysiology.
View Article and Find Full Text PDFSurg Radiol Anat
September 2025
Orthopaedics and Traumathology Department, ULS São João, Porto, Portugal.
Purpose: Pelvic ring fractures involving the iliopubic rami can cause functional impairment. Percutaneous retrograde fixation is a less invasive procedure when compared to traditional open approaches, however precise anatomical knowledge is crucial for safe screw placement. This study aims to describe the morphology of the iliopubic rami, define a safety corridor for percutaneous screw fixation, specially focusing on the relationships between the iliopubic rami and neurovascular structures.
View Article and Find Full Text PDFRadiother Oncol
September 2025
Department of Radiation Oncology, University of Maryland School of Medicine, Baltimore, MD, USA. Electronic address:
Purpose: To predict metastasis-free survival (MFS) for patients with prostate adenocarcinoma (PCa) treated with androgen deprivation therapy (ADT) and external radiotherapy using clinical factors and radiomics extracted from primary tumor and node volumes in pre-treatment PSMA PET/CT scans.
Materials/methods: Our cohort includes 134 PCa patients (nodal involvement in 28 patients). Gross tumor volumes of primary tumor (GTVp) and nodes (GTVn) on CT and PET scans were segmented.
Background: Overweight and obesity are major concerns among people living with HIV (PLWH), particularly those on integrase inhibitors, as they elevate the risk of cardiovascular diseases. However, longitudinal data on the burden and risk factors for overweight/obesity in sub-Saharan Africa (SSA) remain limited. This study aimed to estimate the incidence and identify factors associated with overweight and obesity among PLWH who switched to a dolutegravir (DTG)-based ART regimen at Livingstone University Teaching Hospital.
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