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Perceived safety (PS) and trust are important factors that influence the adoption of autonomous driving. In order to study the factors influencing PS and the possibility of real-time monitoring, an on-road experiment with L2 autonomous driving with 30 participants was conducted. Participants experienced autonomous driving functions as co-drivers and rated PS through video replays. Physiological data were recorded during the experiment and analysed afterwards. It was found that PS significantly reduced during events of hard braking and bumps, whereas it was high during congestions and hard-turning events when speed was relatively lower. Analysis of geolocations and environmental data around the vehicle showed that tunnels, terrain and traffic complexity would impact PS. Physiological data showed a significant negative correlation between electromyogram (EMG) of the lower limb and PS. Through post-experiment interviews, technical and human-computer interaction (HCI) measures that are expected to improve PS are proposed.
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http://dx.doi.org/10.1080/00140139.2025.2534586 | DOI Listing |
Adv Sci (Weinh)
September 2025
Department of Occupational Health (Key Laboratory of Electromagnetic Radiation Protection, Ministry of Education), Army Medical University (Third Military Medical University), Chongqing, 400038, China.
Cadmium (Cd) is a heavy metal that exhibits strong carcinogenic properties and promotes breast cancer (BC) progression. Autophagic flux dysfunction is involved in Cd-induced BC progression, but the underlying molecular mechanisms remain unclear. Here, it is observed that impaired autophagic flux and metabolic reprogramming are notable features related to Cd-induced proliferation, migration, and invasion in BC cell lines, including T-47D and MCF-7 cells.
View Article and Find Full Text PDFSmall Sci
September 2025
Infrared photodetectors are crucial for autonomous driving, providing reliable object detection under challenging lighting conditions. However, conventional silicon-based devices are limited in their responsivity beyond 1100 nm. Here, a scallop-structured silicon photodetector integrated with tin-substituted perovskite quantum dots (PQDs) that effectively extends infrared detection is demonstrated.
View Article and Find Full Text PDFFront Biosci (Landmark Ed)
August 2025
Department of Hepatobiliary Surgery, General Hospital of Ningxia Medical University, 750004 Yinchuan, Ningxia Hui Autonomous Region, China.
Background: Mediator complex subunit 10 (MED10) serves as a critical regulator of eukaryotic gene expression by facilitating RNA polymerase II activity. Our investigation aims to characterize MED10's functional contributions and underlying molecular pathways in hepatocellular carcinoma (HCC) development.
Methods: MED10 expression patterns in HCC and their correlation with clinicopathological parameters and patient outcomes were examined using bioinformatics databases and immunohistochemistry.
CRISPR homing gene drive is a disruptive biotechnology developed over the past decade with potential applications in public health, agriculture, and conservation biology. This technology relies on an autonomous selfish genetic element able to spread in natural populations through the release of gene drive individuals. However, it has not yet been deployed in the wild.
View Article and Find Full Text PDFChem Biol Interact
September 2025
School of Public Health, Ningxia Medical University (Yinchuan City, Ningxia Hui Autonomous Region, China; Key Laboratory of Environmental Factors and Chronic Disease Control, No.1160, the Street of Shengli, Xingqing District, Yinchuan, Ningxia Hui Autonomous Region, China. Electronic address: hmin81
Paraquat (PQ) is characterized by neurotoxicity. In daily life, PQ exposure mainly occurs through chronic and trace pathways, which induce progressive neuronal damage or neuronal synaptic loss. Previously, mitochondrial dysfunction was a critical underlying mechanism.
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