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Background: Two tibial component designs are mainly used in fixed-bearing unicompartmental knee arthroplasty (UKA): metal-backed (MtB) and all-polyethylene (AP). While AP components allow for increased polyethylene thickness with minimal bone resection, MtB implants offer modularity for isolated bearing exchange and potentially superior stress distribution. However, controversy remains regarding their respective revision rates and patient-reported outcome measures (PROMs).
Methods: We conducted a systematic review and meta-analysis following Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines and registered our protocol on International Prospective Register of Systematic Reviews (CRD42024604110). A comprehensive search was performed in PubMed, Web of Science, Embase, and Scopus up to December 10, 2024, without language restrictions. Studies comparing MtB and AP tibial components in medial fixed-bearing UKA were included, assessing revision rates, PROMs, and range of motion (ROM). Data were extracted independently by 2 reviewers, and statistical analysis was performed using a random-effect model. Odds ratios (ORs) were calculated for all-cause revision and aseptic tibial loosening rates, whereas mean differences were calculated for PROMs and ROM.
Results: Sixteen studies involving 34,738 participants (34,998 knees) were included, with 21,097 knees receiving MtB prostheses and 13,836 receiving AP prostheses. The overall all-cause revision and aseptic tibial loosening rates were significantly lower in the MtB group: OR, 0.49; 95% confidence interval (CI), 0.31-0.79; p = 0.003 and OR, 0.29; 95% CI, 0.09-0.99; p = 0.048, respectively. However, PROMs-including Knee Society Score, Knee Society Function Score, Oxford Knee Score, Knee Injury and Osteoarthritis Outcome Score, Short Form-36, and ROM-were comparable between groups.
Conclusion: MtB tibial components in medial fixed-bearing UKA offer comparable PROMs and ROM with significantly lower rates of both all-cause revision and revision because of aseptic tibial component loosening relative to AP designs.
Level Of Evidence: Therapeutic Level III. See Instructions for Authors for a complete description of levels of evidence.
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http://dx.doi.org/10.2106/JBJS.RVW.25.00061 | DOI Listing |
J Am Podiatr Med Assoc
September 2025
§Aybars Kıvrak Orthopedics Clinic, Adana, Turkey.
Background: Pilon fractures refer to distal tibial fractures that may involve extra-articular, partial articular, or complete intra-articular components, most commonly caused by high-energy trauma. The choice between early (<72 hours) and delayed (>7 days) surgical fixation significantly impacts clinical outcomes. This study aimed to compare the effects of early vs.
View Article and Find Full Text PDFKnee Surg Sports Traumatol Arthrosc
September 2025
Department of Orthopaedic Surgery and Traumatology, Ghent University, Ghent, Belgium.
Purpose: Robot-assisted total knee arthroplasty (RATKA) aims to improve surgical precision and outcomes. This study compared clinical and radiological outcomes between RATKA and conventional total knee arthroplasty (CTKA).
Methods: A systematic review was conducted in accordance with PRISMA guidelines, including prospective studies (Level I/II evidence) from MEDLINE, Embase, Web of Science, and the Cochrane Library, up to 20 May 2025.
Int J Numer Method Biomed Eng
September 2025
Joint Reconstruction Research Center, Tehran University of Medical Sciences, Tehran, Iran.
The need for total knee arthroplasty (TKA) has grown significantly in recent years. The cutting angle in TKA plays a major role in the functionality and life expectancy of the knee implant components. This study aims to personalize the femur bone cutting angle selection for implant placement.
View Article and Find Full Text PDFPurpose: Knee osteoarthritis (OA) is the most common degenerative joint disease in the world. It results in not only physical limitation and pain, but also negatively impacts quality of life and mental wellbeing. Treatment options such as medial opening wedge high tibial osteotomy (MOWHTO) help to relieve pain and improve functionality, but there is limited literature on the effect on mental health.
View Article and Find Full Text PDFFASEB J
September 2025
State Key Laboratory of Discovery and Utilization of Functional Components in Traditional Chinese Medicine, School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China.
Restenosis following endovascular intervention in lower extremity arterial disease contributes to significant morbidity and mortality. This study investigates the role of formylpeptide receptor 2 (FPR2) in neointimal hyperplasia and evaluates the therapeutic potential of the selective FPR2 agonist BMS-986235 in mitigating restenosis. FPR2 expression was significantly reduced in the popliteal and anterior tibial arteries of male amputees with restenosis compared to healthy controls.
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