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http://dx.doi.org/10.1016/j.sleep.2025.106673 | DOI Listing |
JAMA Netw Open
September 2025
Perelman School of Medicine, University of Pennsylvania, Philadelphia.
Importance: As obesity rates rise in the US, managing associated metabolic comorbidities presents a growing burden to the health care system. While bariatric surgery has shown promise in mitigating established metabolic conditions, no large studies have quantified the risk of developing major obesity-related comorbidities after bariatric surgery.
Objective: To identify common metabolic phenotypes for patients eligible for bariatric surgery and to estimate crude and adjusted incidence rates of additional metabolic comorbidities associated with bariatric surgery compared with weight management program (WMP) alone.
Ann Am Thorac Soc
September 2025
University of Gothenburg Sahlgrenska Academy, Department of Internal Medicine and Clinical Nutrition, Gothenburg, Sweden.
Introduction: Co-morbid insomnia and sleep apnea (COMISA) has been linked to poorer health outcomes and increased all-cause mortality compared with either insomnia or obstructive sleep apnea (OSA) alone.
Materials And Methods: We investigated the relationship between COMISA and uncontrolled hypertension in the Swedish CardioPulmonary BioImage Study (SCAPIS). A cross-sectional analysis including participants from the SCAPIS Gothenburg cohort (n=3832, 46% males, age 57.
Sleep Adv
July 2025
Waisman Center, University of Wisconsin, Madison, Madison, WI 53705, United States.
This study provided a preliminary examination of indices of obstructive sleep apsnea (OSA) and sleep disruptions in adults with Down syndrome (DS), and their associations with Alzheimer's disease (AD) pathology and symptomatology. A total of 93 adults with DS (aged 25-61 years) from the Alzheimer Biomarker Consortium-DS completed cognitive assessments, MRI and positron emission tomography (PET) scans (assessing amyloid-beta [Aβ] and tau), and a one-night home sleep study using the WatchPAT-300 device. Study partners also reported on depressive symptoms and diagnoses.
View Article and Find Full Text PDFPLoS One
September 2025
Department of Otolaryngology, Tungs' Taichung MetroHarbor Hospital, Taichung, Taiwan.
With an increasing aging population, the prevalence of chronic comorbidities is on the rise. The potential relationship between obstructive sleep apnea (OSA) and osteoporosis has garnered significant attention. Most studies examining the association between these two conditions have relied on dual-energy X-ray absorptiometry (DXA) to evaluate bone mineral density (BMD).
View Article and Find Full Text PDFOrthod Craniofac Res
September 2025
Department of Orthodontics and Pediatric Dentistry, Faculty of Dentistry, University of Szeged, Szeged, Hungary.
Aim: To evaluate the association between vertical and sagittal facial profile characteristics and the diagnosis/severity of Obstructive Sleep Apnea (OSA) based on hospital-based polysomnography (PSG) in children attending their first orthodontic visit.
Materials And Methods: 3671 children aged 7 to 9 years who attended a private practice for a first orthodontic consultation were included. Apnea/Hypopnea Index (AHI) was measured from PSG, while vertical and skeletal facial profile characteristics were assessed according to the Modified Sassouni Analysis on lateral cephalogram.