Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
The aim of this study was to investigate the effects of Familial Mediterranean Fever (FMF) on the choroidal tissue, which has a dense vascular network in the eye. A total of 95 eyes of 45 children diagnosed with FMF with homozygous c.~ (p.M694V) mutation in the MEFV gene and 50 healthy children were included in this prospective cross-sectional study. Optical coherence tomography (OCT) images were obtained from all children. Subfoveal choroidal thickness (SFCT), choroidal vascularity index (CVI) and nasal CT values were significantly lower in the patient group compared to the healthy group ( = 0.004, = 0.002, and = 0.036 respectively). In this study, we observed a significant decrease in both CVI and SFCT in children with FMF compared to healthy controls. This finding suggests that FMF disrupts choroidal structures in the eye, consistent with its known pathophysiology. Although there are no observable pathological findings, the decrease in SFCT and CVI values emphasizes the need for more frequent follow-up and more careful treatment of these children.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1080/09273948.2025.2532824 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Edwards syndrome: Neurocognitive and linguistic profile, diagnosis, overlaps and treatment.
Pol Merkur Lekarski
September 2025
NEAPOLIS UNIVERSITY, NEAPOLIS, CYPRUS.
Objective: Aim: To provide a comprehensive understanding of the profound developmental and medical challenges associated with this condition..
Patients And Methods: Materials and Methods: Τhis study employed a narrative review methodology, drawing upon a wide range of peer-reviewed scientific literature, clinical guidelines, and case studies.
Models of care for children and adolescents with type 1 diabetes in low- and middle-income countries: a scoping review.
Cochrane Database Syst Rev
September 2025
Cochrane Evidence Synthesis Unit Germany/UK - Sub-Unit Düsseldorf, Institute of General Practice, Centre for Health and Society, Medical Faculty of the Heinrich-Heine-University Düsseldorf, Düsseldorf, Germany.
Background: In order to improve the outcomes of children and adolescents with type 1 diabetes mellitus (T1DM), access to and quality of comprehensive acute and chronic care services in low- and middle-income countries (LMIC) must be improved.
Objectives: To identify and summarise the characteristics of models of care for T1DM in children and adolescents in LMIC.
Search Methods: We searched MEDLINE, Scopus, the Cochrane Central Register of Controlled Trials (CENTRAL), and the World Health Organization (WHO) Global Index Medicus from inception to 11 December 2023 without restrictions.
Mevalonate kinase deficiency in a familial Mediterranean fever endemic region: a single-center experience.
Turk J Pediatr
September 2025
Division of Pediatric Rheumatology, Department of Pediatrics, Cerrahpaşa Faculty of Medicine, İstanbul University-Cerrahpaşa, İstanbul, Türkiye.
Background: We aimed to document childhood onset mevalonate kinase deficiency (MKD) and to explore treatment responses and diagnostic challenges in regions endemic to familial Mediterranean fever (FMF).
Methods: This retrospective study included patients under 18 years of age, diagnosed with MKD and followed for at least six months at the pediatric rheumatology department of Istanbul University - Cerrahpaşa Medical Faculty between 2016 and 2024.
Results: Of 33 patients, 51.
A structural equation modeling approach to examine determinants of nutritional status in Palestinian children 6-59 months.
PLoS One
September 2025
Department of Medicine, Al-Quds University, Jerusalem, Palestine.
Background: Undernutrition remains a persistent public health concern among young children in Palestine, shaped by a range of socioeconomic and dietary factors. This study applies a Structural Equation Modeling (SEM) approach to explore both direct and indirect determinants of child growth among children aged 6-59 months in the West Bank.
Methods: Data were drawn from a 2022 cross-sectional survey involving 300 children selected from 1,400 households.
Healthy dietary pattern and risk of rheumatoid arthritis: A systematic review and meta-analysis.
Semin Arthritis Rheum
August 2025
Division of Rheumatology, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA; Department of Quantitative Health Sciences, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA. Electronic address:
Objectives: We aimed to determine the degree to which a healthy dietary pattern is associated with incident rheumatoid arthritis (RA).
Methods: We registered this systematic review and meta-analysis in PROSPERO (CRD42025645056). Inclusion criteria were validated diet (anti-inflammatory, Mediterranean, Dietary Approaches to Stop Hypertension (DASH), and/or healthy eating index [HEI]); validated RA definition; dietary exposure preceding RA; and randomized controlled trial, cohort, or case-control design.