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Introduction Uganda's Community-Led Total Sanitation (CLTS) strategy is based on the use of health extension workers (HEWs) for its implementation at the community level. However, identification of other facilitators to improve and accelerate the scaling up of the CLTS intervention has not been explored. This study evaluated the effect of a student-led CLTS intervention on open defecation and open defecation-free status outcomes. Methods The study was conducted in two sub-counties in Kabale district in southwestern Uganda, Rubaya and Buhara. We used a pre-post study with a nonequivalent control group quasi-experimental study design to measure the effect of a student-led CLTS intervention on' the levels of household open defecation (OD)-free (HODF) status. A total of six parishes from two study sub-counties with no main towns and having low latrine coverage were selected. A total of 50 villages were randomly selected, and 25 villages were assigned to each of the two study groups: (i) the student-led CLTS intervention group, and (ii) the conventional CLTS control group. To avoid contamination between the sub-counties, a buffer sub-county was left between. A total of 492 respondents from different households participated in the before and after CLTS intervention surveys. Results In the intervention group, the proportion of households practicing OD decreased (24.69% to 14.04%), and the households that obtained the HODF status also increased (2.88% to 6.14%). On the other hand, in the control group, OD increased (23.69% to 39.92%), and households with HODF status reduced (3.21% to 0.84%). The results showed that the households in the intervention group had higher odds of not practicing OD (OR 3.73; 95%CI: 1.01-13.77) compared to the households in the control group. Similarly, in the intervention group, households had a higher odds of attaining the HODF status (OR 13.20; 95%CI: 3.26- 53.55) compared to the control group. Conclusion The student-led CLTS reduced OD in the parishes where they worked. This study shows that other resource persons, such as health profession students, are a valuable resource that can fill in the gap in sanitation promotion activities. They will be able to successfully complement the already overburdened health workers, as in the case of Uganda.
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http://dx.doi.org/10.7759/cureus.85858 | DOI Listing |
Pest Manag Sci
September 2025
Laboratory of Applied Entomology, Graduate School of Horticulture, Chiba University, Chiba, Japan.
Background: The coevolutionary arms race between echolocating bats and tympanate moths has driven the evolution of ultrasound-mediated escape behaviors in moths. Bat-emitted ultrasonic pulses vary in sound intensity and temporal structure, with pulse repetition rate (PRR) which intrinsically encode critical information about predation risk, i.e.
View Article and Find Full Text PDFInt J Gen Med
September 2025
Department of Pediatric, The Affiliated Hospital to Changchun University of Chinese Medicine, Changchun, Jilin, 130000, People's Republic of China.
Background: Mycoplasma pneumoniae pneumonia (MPP) is a common respiratory infection in children, current treatments are limited by resistance and side effects. This study aims to evaluate the clinical efficacy and safety of combining Qingke Mixture with azithromycin for treating MPP in children.
Methods: This prospective, randomized, double-blind, controlled trial included 92 children diagnosed with MPP.
Curr Dev Nutr
September 2025
Department of Health, Nutrition, and Food Sciences, Florida State University, Tallahassee, FL, United States.
Background: The objective of this study was to compare the effects of daily consumption of white potatoes compared with white rice on cardiometabolic health in individuals with type-2 diabetes (T2D).
Objective: To determine the effects of white potato consumption compared to white rice (a commonly consumed refined grain) on indices of glycemic control and cardiovascular health in individuals with overweight or obesity and T2D.
Methods: In this randomized crossover study, comparative control trial, 24 adults with T2D [45-80 y, body mass index (kg/m) 25-40] consumed baked white potatoes (100 g) or calorie-matched white rice (75 g) daily for 12 wk, separated by a 2-wk washout, with assessments of glycemic control, lipids, inflammation, blood pressure, endothelial function, and body composition at baseline (only 1 baseline visit included as a covariate in statistical analyses), 6 wk, and 12 wk.
Med Acupunct
August 2025
Faculty of Medicine, Universitas Sebelas Maret, Surakarta, Indonesia.
Introduction: Acupuncture has emerged as an effective adjunctive therapy for polycystic ovary syndrome (PCOS) with concern on the higher rate of adverse events (AE). In addition, timing of intervention, specific acupoints, and stimulation strength are concerning, as high-stimulation electroacupuncture (EA) may increase miscarriage risk. This review aims to systematically evaluate the safety profile of acupuncture in PCOS.
View Article and Find Full Text PDFFront Immunol
September 2025
Guangxi Key Laboratory of AIDS Prevention and Treatment & School of Public Health, Guangxi Medical University, Nanning, Guangxi, China.
Background: People living with HIV(PLWH) are a high-risk population for cancer. We conducted a pioneering study on the gut microbiota of PLWH with various types of cancer, revealing key microbiota.
Methods: We collected stool samples from 54 PLWH who have cancer (PLWH-C), including Kaposi's sarcoma (KS, n=7), lymphoma (L, n=22), lung cancer (LC, n=12), and colorectal cancer (CRC, n=13), 55 PLWH who do not have cancer (PLWH-NC), and 49 people living without HIV (Ctrl).