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http://dx.doi.org/10.5114/aic.2025.151706 | DOI Listing |
JACC Case Rep
August 2025
Division of Cardiology, The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Background: Iatrogenic coronary artery dissection is a rare but potentially catastrophic complication of coronary angiography. Coronary artery dissection can lead to cardiogenic shock and cardiac arrest.
Case Summary: A 54-year-old man presented with a non-ST-segment elevation myocardial infarction and was found to have severe stenosis of the obtuse marginal artery and right coronary artery.
Neurochem Res
August 2025
Department of Otorhinolaryngology, Head and Neck Surgery, Charité- Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, 10117, Berlin, Germany.
The histamine H3 receptor (H3R) is a crucial regulator of synaptic plasticity, neurotransmitter release, and neural signaling within the central nervous system. However, its role in the cochlea remains poorly understood, even though mast cells, a rich endogenous source of histamine, have recently been documented in the mammalian cochlea. This study examined H3R expression and localization in the postnatal day 4-5 (P4-5) C57BL/6 mouse cochlea and evaluated its functional consequences under antagonist treatment.
View Article and Find Full Text PDFSensorineural hearing loss (SNHL) seriously affects people's lives, and the degradation of spiral ganglion neurons (SGNs) is the main cause of SNHL. Many studies have revealed that long non-coding RNAs (lncRNAs) are linked to SGNs. However, it is still unclear how lncRNAs affect damage repair in SGNs.
View Article and Find Full Text PDFAntioxidants (Basel)
July 2025
Obstetrics & Gynecology Hospital of Fudan University, Shanghai 200433, China.
Preeclampsia (PE) is a pregnancy-specific hypertensive disorder characterized by systemic inflammation, endothelial dysfunction, and placental insufficiency. While inadequate trophoblast invasion and impaired spiral artery remodeling have long been recognized as central to its pathogenesis, emerging evidence underscores the critical roles of dysregulated iron metabolism and its crosstalk with immune responses, particularly macrophage-mediated inflammation, in driving PE development. This review systematically explores the dynamic changes in iron metabolism during pregnancy, including increased maternal iron demand, placental iron transport mechanisms, and the molecular regulation of placental iron homeostasis.
View Article and Find Full Text PDFPostepy Kardiol Interwencyjnej
June 2025
Division of Interventional Cardiology, Cardiovascular Diseases Department, University Hospital of Split, Split, Croatia.