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http://dx.doi.org/10.1007/s00018-025-05762-1 | DOI Listing |
Math Biosci
August 2025
Department of Mathematics, University of Sussex, Brighton BN1 9QH, UK.
RNA viruses are known for their fascinating evolutionary dynamics, characterised by high mutation rates, fast replication, and ability to form quasispecies - clouds of genetically related mutants. Fast replication in RNA viruses is achieved by a very fast but error-prone RNA-dependent RNA polymerase (RdRP). High mutation rates are a double-edged sword: they provide RNA viruses with a mechanism of fast adaptation to a changing environment or host immune system, but at the same time they pose risk to virus survivability in terms of either virus population being dominated by mutants (error catastrophe), or extinction of all viral sequences due to accumulation of mutations (lethal mutagenesis).
View Article and Find Full Text PDFExp Biol Med (Maywood)
July 2025
Ph.D. Program in Regulatory Science and Policy, National Yang-Ming Chiao-Tung University, Hsin-Chu, Taiwan.
[This corrects the article DOI: 10.3389/ebm.2025.
View Article and Find Full Text PDFCell Mol Life Sci
July 2025
College of Veterinary Medicine, Nanjing Agricultural University, Wei gang 1, Nanjing, Jiangsu, 210095, China.
Spine J
August 2025
Department of Spine Surgery, Hospital for Special Surgery, New York, NY, USA. Electronic address:
Background Context: Generative artificial intelligence (AI), ChatGPT being the most popular example, has been extensively assessed for its capability to respond to medical questions, such as queries in spine treatment approaches or technological advances. However, it often lacks scientific foundation or fabricates inauthentic references, also known as AI hallucinations.
Purpose: To develop an understanding of the scientific basis of generative AI tools by studying the authenticity of references and reliability in comparison to the alignment of responses of evidence-based guidelines.