98%
921
2 minutes
20
Description In this review, we critically evaluate the Food and Drug Administration's modified risk tobacco product (MRTP) status granted to a smokeless tobacco product (March 2023), Copenhagen Classic Snuff (CCS). This new status necessitates an assessment of the product CCS use and its public health impacts. We assess the impact of CCS as it relates to the reduction of lung cancer risk and the potential increased risk for nasopharyngeal cancer, chronic rhinitis, nicotine dependence, and other health hazards. Concerns persist regarding nicotine's harm and public misperception due to risk reclassification, and caution should be maintained to discourage novel snuff users. Advocating prudent interpretation of MRTP status and comprehensive post-market surveillance is necessary for critical assessment by health care professionals and consumers.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12240401 | PMC |
http://dx.doi.org/10.36518/2689-0216.1832 | DOI Listing |
Pestic Biochem Physiol
November 2025
Tianjin Key Laboratory of Structure and Performance for Functional Molecules, College of Chemistry, Tianjin Normal University, Tianjin 300387, China. Electronic address:
The extensive use of highly toxic and residual pesticides has a significant negative impact on agricultural production and the ecological environment. The development of new green antiviral agents has become a major demand for ensuring the development of green ecological agriculture. Indole alkaloids are widely present in nature and have diverse biological activities.
View Article and Find Full Text PDFDermatol Ther (Heidelb)
September 2025
Department of Dermatology, Kyoto University, Kyoto, Japan.
Atopic dermatitis (AD) is a chronic inflammatory disease characterized by eczematous skin lesions, intense pruritus, skin pain, sleep disruption, and mental health disturbances. There remains a need for a therapeutic option that delivers durable efficacy, safety, and convenient dosing across the AD patient population. This review provides an overview of AD pathogenesis driven by T-cell imbalance and describes a novel therapeutic option targeting the OX40 receptor, a costimulatory molecule expressed specifically on activated T cells.
View Article and Find Full Text PDFCarbohydr Polym
November 2025
Flavors and Fragrance Engineering & Technology Research Center of Henan Province, College of Tobacco Science, Henan Agricultural University, Zhengzhou 450000, China. Electronic address:
Fragrances are indispensable additives in consumer products including foods, cosmetics, and tobacco products. However, their inherent instability leads to rapid quality degradation and performance loss, driving the urgent need for controlled-release systems to stabilize fragrance performance. In this work, cellulose nanofibers (CNF) were used to prepare CNF aerogel-like gels (CA) and carbonized CNF aerogels (C-CA) through freeze-drying and high-temperature carbonization.
View Article and Find Full Text PDFJ Am Acad Orthop Surg
August 2025
From the Department of Medical Education, Texas A&M College of Medicine, Dallas, TX (Sontam, Toussaint, Hlavinka, Chavda, and Mbilinyi), and the Department of Orthopedic Surgery, Baylor University Medical Center, Dallas, TX (Zide).
Background: Smoking is a well-established risk factor for postoperative complications following open reduction and internal fixation (ORIF) for rotational ankle fractures. However, the effect of non-tobacco nicotine (NTN) use on these outcomes remains unclear, despite the increasing use of products such as vapes. This retrospective cohort study investigates whether perioperative NTN use is associated with increased postoperative complications following ankle ORIF compared with a nicotine-independent (NI) control group.
View Article and Find Full Text PDFNicotine Tob Res
September 2025
National Institute on Drug Abuse, 6001 Executive Blvd, N. Bethesda, Maryland 20852.
Introduction: Flavors play an important role in e-cigarette use among both young people and adults, but evaluations of flavored e-cigarette policies have focused almost exclusively on youth. This longitudinal study examined how flavored e-cigarette policies affect tobacco use over time for different adult age groups using data from the Population Assessment of Tobacco and Health (PATH) Study.
Methods: Adults age 21+ at Wave 5 (2018-2019) comprised the analytic sample.