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BackgroundMechanical thrombectomy (MT) is the gold standard treatment for acute ischemic stroke (AIS) patients with large vessel occlusion. Direct cervical carotid puncture is a recognized approach in unfavorable aortic arch anatomy. However, manual compression/ surgical closure of the access site can be challenging if the International Normalized Ratio (INR) is high and the patient is taking anticoagulation.Case SummaryWe present a case of Stanford type A (STA) aortic dissection (status post Bentall procedure) presenting with acute ischemic stroke (AIS) with left M2-MCA thrombotic occlusion. Conventional transfemoral or transradial approach for MT was deferred due to replaced ascending aorta & arch debranching and a residual thoraco-abdominal aortic dissection flap. Risk of soft tissue blood loss was high with open neck access (surgical cut down) due to high INR of 2.9. So, MT was performed through direct left common carotid artery (CCA) puncture achieving mTICI 3 flow. Due to high INR, manual compression was deferred, puncture site haemostasis was achieved with use of collagen based Obtura vascular closure device (VCD). Patient made substantial neurological recovery with no puncture site complications and MRS-0 at discharge.ConclusionObtura femoral VCD can be an alternative haemostatic device for direct carotid puncture mechanical thrombectomy for AIS.
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http://dx.doi.org/10.1177/15385744251360827 | DOI Listing |
Adv Sci (Weinh)
August 2025
Department of Sports Medicine of the Second Affiliated Hospital, and Liangzhu Laboratory, Zhejiang University School of Medicine, Hangzhou, 310058, China.
Achieving strong adhesion under wet and bleeding conditions remains a major challenge for medical adhesives. Existing strategies that utilize polymer chain penetration to overcome this have shown promise but typically rely on complex external stimuli, limiting clinical use. Here, MonoSeal is introduced, a body-fluid-triggered adhesive sponge composed of a single oxidized polysaccharide, operating via a newly proposed mechanism termed Autopenetrative Adhesion (APA).
View Article and Find Full Text PDFEur J Med Res
August 2025
Department of Graduate School, Hebei Medical University, Shijiazhuang, 050011, Hebei, China.
Introduction: This study aimed to elucidate the impact of the first-pass effect (PFE) on patients with acute terminal internal carotid artery occlusion.
Methods: We conducted a retrospective analysis of patients with acute terminal internal carotid artery occlusion who underwent endovascular treatment. PFE was defined as achieving complete revascularization with a single use of the thrombectomy device, without the requirement for salvage therapy during the procedure.
J Neuroendovasc Ther
August 2025
Department of Neurosurgery, Hyogo Prefectural Amagasaki General Medical Center, Amagasaki, Hyogo, Japan.
Objective: This case report describes the successful coil embolization of a direct carotid-cavernous fistula (d-CCF) caused by aneurysmal rupture in an older patient with residual aortic dissection, via direct puncture of the common carotid artery (CCA).
Case Presentation: A 95-year-old woman presented with progressive right periorbital swelling, pain, and eye redness. Cranial imaging revealed proptosis, dilated superior and inferior ophthalmic veins, and a ruptured aneurysm of the right internal carotid artery (ICA), leading to a diagnosis of d-CCF.
Introduction Although endovascular treatment (EVT) for large vessel occlusion (LVO) generally yields better outcomes in younger patients compared to older individuals, the efficacy of this intervention and the age-related variations in factors influencing outcomes remain insufficiently elucidated. This study aims to compare the outcomes of EVT between younger and older patients and to investigate the factors associated with favorable outcomes, with a particular focus on the relationship between procedural time and clinical results. Method The K-NET Registry comprised 3,187 EVT cases.
View Article and Find Full Text PDFInterv Neuroradiol
July 2025
Department of Neurosurgery, University of Rochester Medical Center, Rochester, NY, USA.
BackgroundDelivery assist catheters are a new class of devices designed to better navigate tortuous segments and reach the clot interface in mechanical thrombectomy. The RED 72 aspiration catheter with SENDit technology is one such example. SENDit is a novel tapered obturator used instead of a microcatheter to bring up the RED 72.
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