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Fluoride is a naturally occurring element found in the environment. However, excessive exposure to fluoride can lead to fluoride toxicity, posing serious risk to human health, plant growth, aquatic animals, and microorganisms. Prolonged exposure to high levels of fluoride can cause dental and skeletal fluorosis, causing brittle bones, joint pain, and damaged enamel. In plants, fluoride accumulation causes stunted growth, chlorosis, and reduced photosynthesis, significantly affecting crop yields and ecosystem health. Bioremediation has emerged as a sustainable eco-friendly approach to mitigating fluoride toxicity. In addition, biofilm technology has shown promise as an innovative tool for pollutant remediation. This review explores the pathway, mechanism, and the effect of fluoride on humans, plants and microbes. It also examines the potential of bioremediation of fluoride degradation with a particular focus on recent advancements in microbial and phytoremediation and their effectiveness in reducing fluoride toxicity. By providing insights into these remediation strategies, this review aims to support informed decision regarding water quality management, agricultural practices, industrial regulations, and public health, particularly in fluoride-contaminated region.
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http://dx.doi.org/10.1007/s00284-025-04365-0 | DOI Listing |
Comp Biochem Physiol C Toxicol Pharmacol
September 2025
Department of Biotechnology, Bharathiar University, Coimbatore, Tamil Nadu, India. Electronic address:
Excessive fluoride (F) exposure, particularly during early development, poses a significant risk to skeletal integrity by disrupting bone homeostasis through oxidative stress and altered mineralization. While F induced oxidative stress is well documented, studies investigating the role of natural antioxidants in mitigating F induced osteochondral toxicity remains limited. Hence, the present study investigated the osteomodulatory effect of fisetin (Fis) against F toxicity in zebrafish larvae.
View Article and Find Full Text PDFEnviron Res
September 2025
School of Resources and Safety Engineering, University of Science and Technology Beijing, Beijing 100083, China; Key Laboratory of Safe and Green Mining of Metal Mines with Cemented Paste Backfill, National Mine Safety Administration, University of Science and Technology Beijing, Beijing 100083, Chi
Cemented paste backfill has made outstanding contributions to the large-scale consumption of phosphogypsum (PG), but poor water resistance significantly weakens the mechanical strength, promotes the leaching of total soluble phosphate (TP) and fluoride ions (F), and reduces its attractiveness in mine engineering. This research synthesized a curing agent (CA) using sodium methylsilicate, sodium silicate, and polyaluminum chloride (PAC). PG produced from Deyang Haohua Qingping Phosphate Mine Co.
View Article and Find Full Text PDFBisphenol A (BPA) and its analogs are collectively termed bisphenol compounds (BPs), which are predominantly utilized in the manufacturing of polycarbonate plastics and epoxy resins. BPs are ubiquitous in diverse environmental matrices, human tissues, and metabolic products. Extensive research has demonstrated that BPs exert adverse effects on the nervous, reproductive, immune, and metabolic systems.
View Article and Find Full Text PDFACS Sustain Chem Eng
September 2025
Electrochemical Innovation Lab, Department of Chemical Engineering, University College London, Torrington Place, London WC1E 7JE, U.K.
Traditionally, binders such as poly-(vinylidene fluoride) (PVDF) have been used within lithium-sulfur (Li-S) batteries, but these present environmental and recyclability challenges and have little to no impact on the processes that drive degradation in the cell's chemistry. Ideally, a Li-S battery binder would contribute to the mitigation of the polysulfide shuttle effect and negate the impacts of positive electrode volume expansion while being compatible with aqueous ink preparation and low-energy, low-toxicity recycling processes. In this work, we demonstrate that fibroin, an economical and sustainable biological polymer with an abundance of functional groups, can effectively trap polysulfides while still offering the durability, cyclability, and ease of use offered by the current state-of-the-art binder (PVDF).
View Article and Find Full Text PDFACS Appl Mater Interfaces
September 2025
Departamento de Física - FFCLRP, Universidade de São Paulo, Ribeirão Preto, SP 14040-901, Brazil.
We synthesized europium-doped gadolinium fluoride (GdF:Eu) scintillating nanoparticles conjugated to methylene blue (MB) for singlet oxygen (O) generation in X-ray-induced photodynamic therapy (X-PDT). The impact of MB conjugation on GdF:Eu nanoparticles (GdF@B) was analyzed, including size, polydispersity, and surface charge. Time-resolved photoluminescence analysis demonstrated that binding of MB to the nanoparticle surface is essential for enabling efficient resonant energy transfer (ET) from the GdF:Eu core to the MB molecules.
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