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Hospital pharmacists frequently face significant job stress, adversely impacting their well-being. Work schedule flexibility is often proposed as a potential buffer against job stress, yet its effectiveness among hospital pharmacists remains understudied. This study investigates the moderating effect of work schedule flexibility on the relationship between job stress and well-being among hospital pharmacists in Punjab, Pakistan. A cross-sectional survey was conducted between September 2023 and January 2024, involving 414 pharmacists working in public hospitals in Punjab province. The study utilized standardized scales to measure well-being, stress levels, and work schedule flexibility among the participants. Bivariate correlation and multiple regression analyses examined the relationships and interaction effects among the study variables. Bivariate correlation analysis revealed a negative association between job stress and well-being, a positive association between work schedule flexibility and well-being, and a negative association between work schedule flexibility and job stress. Multiple regression analysis indicated that work schedule flexibility significantly moderated the relationship between job stress and well-being, with the interaction term showing a significant effect. The findings underscore the importance of work schedule flexibility in mitigating the negative effects of job stress on the well-being of hospital pharmacists. Implementing policies that enhance work schedule flexibility may serve as an effective strategy to improve pharmacists' well-being and job satisfaction. Further research is needed to explore these dynamics in healthcare settings and among diverse professional groups.
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http://dx.doi.org/10.1038/s41598-025-10523-y | DOI Listing |
Occup Environ Med
September 2025
Department of Psychosocial Research and Epidemiology, The Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands
Objectives: Night shift work has been classified as probably carcinogenic to humans, possibly related to suppression of melatonin secretion. Although experimental studies suggest that melatonin inhibits intestinal tumor proliferation, epidemiological evidence for a relationship between night shift work and colorectal cancer (CRC) risk is lacking.
Methods: We prospectively examined the association between night shift work and CRC in the Nightingale Study.
Metab Syndr Relat Disord
September 2025
Yale School of Medicine, New Haven, Connecticut, USA.
Poor sleep has been identified as a strong risk factor for metabolic syndrome. Shift workers, who often experience reduced and misaligned sleep due to nighttime work schedules, are particularly susceptible to both sleep disturbances and metabolic syndrome. However, the interplay among shift work, sleep disturbances, and metabolic syndrome remains insufficiently explored.
View Article and Find Full Text PDFJ Affect Disord
September 2025
Department of Psychology, Indiana University Indianapolis, 402 N. Blackford St., LD 100E, Indianapolis, IN, USA. Electronic address:
Background: Integrating digital mental health into collaborative care could address multiple mental health factors. To determine the longer-term effects of modernized collaborative care for depression on overlapping mental health factors, we analyzed data from the eIMPACT trial.
Methods: Primary care patients with depression and elevated cardiovascular disease risk (N = 216, Mage: 59 years, 78 % female, 50 % Black, 46 % with income <$10,000/year) were randomized to 12 months of the eIMPACT intervention (modernized collaborative care involving internet cognitive-behavioral therapy [iCBT], telephonic CBT, and/or select antidepressants) or usual primary care for depression.
JMIR Form Res
September 2025
Department of Medicine, Duke Global Health Institute, Duke University, Durham, NC, United States.
Background: The global penetration of mobile phones has offered novel opportunities for communicating health-related information to individuals. A low-cost system that facilitates autonomous communication with individuals via mobile phones holds potential for expanding the reach of health messaging in settings with human resource and infrastructure limitations.
Objective: We sought to design a flexible, low-code system using open-source software that could be adapted to different contexts and technical environments and accommodate a wide range of automation needs.
Cureus
August 2025
Psychiatry and Behavioral Sciences, West Virginia University, Morgantown, USA.
This study examined whether caregivers of male or female patients with epilepsy differ in perceived burden, social support, and coping mechanisms. In a cross-sectional design conducted at a tertiary neuropsychiatric hospital, 60 caregivers (30 per group) completed the Family Burden Interview Schedule (FBIS), the Social Support Questionnaire (SSQ), and the Ways of Coping Questionnaire (WCQ). Caregivers of female patients reported greater financial strain and more pronounced impacts on mental and physical health, yet they also perceived higher levels of social support.
View Article and Find Full Text PDF