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Background: Purulent pericarditis is a rare but life-threatening complication of endobronchial ultrasound-guided fine-needle aspiration (EBUS-FNA) of intrathoracic lesions.
Case Summary: A 65-year-old man with hypertension and hearing loss presented with an aggressive case of purulent pericarditis leading to cardiac tamponade post-EBUS-FNA of a station 4R lymph node. Transthoracic echocardiogram demonstrated fibrinous stranding and tamponade physiology. Pericardiocentesis drained over 500 mL of purulent fluid positive for Streptococcus mitis. The patient was successfully managed with a prolonged course of culture-guided intravenous antibiotics.
Discussion: To our knowledge, this is the first reported case of S. mitis purulent pericarditis post-EBUS-FNA.
Take-home Message: This case highlights the differential diagnosis of chest pain in patients undergoing EBUS-FNA and the utility of transthoracic echocardiography in the diagnosis of effusion-constrictive pericarditis.
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http://dx.doi.org/10.1016/j.jaccas.2025.103869 | DOI Listing |
J Cancer Res Ther
September 2025
Department of Gynaecology and Obstetrics, Qilu Hospital of Shandong University, Jinan, Shandong, China.
Esophageal pericardial fistula is a rare complication of esophageal cancer. This article reports the first documented case of an esophageal pericardial fistula following radiotherapy in the presence of an esophageal stent. A 62-year-old man with advanced esophageal and cardiac cancer underwent radiotherapy after esophageal stent placement and subsequently developed an esophageal pericardial fistula.
View Article and Find Full Text PDFWorld J Clin Cases
September 2025
Department of Internal Medicine, University of Nebraska College of Medicine, Omaha, NE 68198, United States.
Background: Pericarditis is the inflammation of the pericardial sac due to a variety of stimuli that ultimately trigger a stereotyped immune response. This condition accounts for up to 5% of emergency department visits for nonischemic chest pain in Western Europe and North America. The most common symptoms of clinical presentation are chest pain and shortness of breath with associated unique electrocardiographic changes.
View Article and Find Full Text PDFCase Rep Cardiol
August 2025
Department of Interventional Cardiology, Marshall University, Huntington, West Virginia, USA.
Purulent pericarditis is a rare, life-threatening condition that has become exceedingly uncommon due to widespread use of antibiotics. However, immunocompromised patients remain susceptible to such opportunistic infections. It is typically caused by direct extension or hematogenous spread from a secondary bacterial source.
View Article and Find Full Text PDFFront Cardiovasc Med
August 2025
Department of Cardiovascular Medicine, Cardiovascular Research Center, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Background: Purulent pericarditis is an infectious condition characterized by purulent pericardial effusion.
Case Presentation: In this case report, we present a 60-year-old male admitted with intermittent chest pain and fever, ultimately diagnosed with primary purulent pericarditis. Imaging revealed an eccentric loculated pericardial effusion, posing significant challenges for conventional pericardiocentesis.
JACC Case Rep
July 2025
Cleveland Clinic, Abu Dhabi, United Arab Emirates. Electronic address:
Background: Septic pericarditis is a rare but life-threatening condition that can mimic acute coronary syndrome (ACS).
Case Summary: A 45-year-old man with diabetes and hypertension presented with acute chest pain and hypotension. Initial electrocardiogram raised suspicion for ACS; however, coronary angiography showed no coronary artery disease.