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Article Abstract

Background: Purulent pericarditis is a rare but life-threatening complication of endobronchial ultrasound-guided fine-needle aspiration (EBUS-FNA) of intrathoracic lesions.

Case Summary: A 65-year-old man with hypertension and hearing loss presented with an aggressive case of purulent pericarditis leading to cardiac tamponade post-EBUS-FNA of a station 4R lymph node. Transthoracic echocardiogram demonstrated fibrinous stranding and tamponade physiology. Pericardiocentesis drained over 500 mL of purulent fluid positive for Streptococcus mitis. The patient was successfully managed with a prolonged course of culture-guided intravenous antibiotics.

Discussion: To our knowledge, this is the first reported case of S. mitis purulent pericarditis post-EBUS-FNA.

Take-home Message: This case highlights the differential diagnosis of chest pain in patients undergoing EBUS-FNA and the utility of transthoracic echocardiography in the diagnosis of effusion-constrictive pericarditis.

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Source
http://dx.doi.org/10.1016/j.jaccas.2025.103869DOI Listing

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