Expression of Concern.

The Publisher, in agreement with the Editor-in-Chief, is issuing this Expression of Concern to inform readers that a formal investigation is currently underway regarding a set of published articles. Despite multiple attempts to contact the corresponding authors, we have not received any response to date. Further editorial actions, such as retraction or correction, will be taken as appropriate in due course. The articles under investigation fall into the following categories. These studies report extended follow-up periods, yet were published prior to the actual conclusion of the declared follow-up. This discrepancy raises serious concerns about the validity of the timeline and outcome reporting: Liao Y, Cheng S, Xiang J, Luo C. lncRNA CCHE1 increased proliferation, metastasis and invasion of non-small lung cancer cells and predicted poor survival in non-small lung cancer patients. Eur Rev Med Pharmacol Sci. 2018 Mar;22(6):1686-1692. doi: 10.26355/eurrev_201803_14581. PMID: 29630113. Yao N, Sun JQ, Yu L, Ma L, Guo BQ. LINC00968 accelerates the progression of epithelial ovarian cancer via mediating the cell cycle progression. Eur Rev Med Pharmacol Sci. 2019 Jun;23(11):4642-4649. doi: 10.26355/eurrev_201906_18043. PMID: 31210289. Hao XZ, Yang K. LncRNA MAGI2-AS3 suppresses the proliferation and invasion of non-small cell lung carcinoma through miRNA-23a-3p/PTEN axis. Eur Rev Med Pharmacol Sci. 2019 Sep;23(17):7399-7407. doi: 10.26355/eurrev_201909_18848. PMID: 31539127. Jiang J, Wu RH, Zhou HL, Li ZM, Kou D, Deng Z, Dong M, Chen LH. TGIF2 promotes cervical cancer metastasis by negatively regulating FCMR. Eur Rev Med Pharmacol Sci. 2020 Jun;24(11):5953-5962. doi: 10.26355/eurrev_202006_21488. PMID: 32572908. These articles have been questioned as they appear to reuse identical or similar graphical elements and images from a shared library across multiple unrelated studies: Xu CF, Liu P, Tan J, Hu DF. Long noncoding RNA LINC00052 suppressed the proliferation, migration and invasion of glioma cells by upregulating KLF6. Eur Rev Med Pharmacol Sci. 2019 Jun;23(11):4822-4827. doi: 10.26355/eurrev_201906_18068. PMID: 31210314. Zheng FX, Wang XQ, Zheng WX, Zhao J. Long noncoding RNA HOXA-AS2 promotes cell migration and invasion via upregulating IGF-2 in non-small cell lung cancer as an oncogene. Eur Rev Med Pharmacol Sci. 2019 Jun;23(11):4793-4799. doi: 10.26355/eurrev_201906_18064. PMID: 31210310. Liao J, Xie N. Long noncoding RNA DSCAM-AS1 functions as an oncogene in non-small cell lung cancer by targeting BCL11A. Eur Rev Med Pharmacol Sci. 2019 Feb;23(3):1087-1092. doi: 10.26355/eurrev_201902_16998. PMID: 30779076. Lu J, Xu FQ, Guo JJ, Lin PL, Meng Z, Hu LG, Li J, Li D, Lu XH, An Y. Long noncoding RNA GAS5 attenuates cardiac fibroblast proliferation in atrial fibrillation via repressing ALK5. Eur Rev Med Pharmacol Sci. 2019 Sep;23(17):7605-7610. doi: 10.26355/eurrev_201909_18883. PMID: 31539152. Shi JQ, Wang B, Cao XQ, Wang YX, Cheng X, Jia CL, Wen T, Luo BJ, Liu ZD. Circular RNA_LARP4 inhibits the progression of non-small-cell lung cancer by regulating the expression of SMAD7. Eur Rev Med Pharmacol Sci. 2020 Feb;24(4):1863-1869. doi: 10.26355/eurrev_202002_20364. PMID: 32141555. Cui K, Zhang H, Wang GZ. MiR-483 suppresses cell proliferation and promotes cell apoptosis by targeting SOX3 in breast cancer. Eur Rev Med Pharmacol Sci. 2019 Mar;23(5):2069-2074. doi: 10.26355/eurrev_201903_17248. PMID: 30915751. Ren L, Zhai H, Wang XL, Li JZ, Xia YH. Hsa_circ_0011946 promotes the migration and invasion of hepatocellular carcinoma by inducing EMT process. Eur Rev Med Pharmacol Sci. 2020 Feb;24(3):1108-1115. doi: 10.26355/eurrev_202002_20161. PMID: 32096173. Chen RX, Liu HL, Yang LL, Kang FH, Xin LP, Huang LR, Guo QF, Wang YL. Circular RNA circRNA_0000285 promotes cervical cancer development by regulating FUS. Eur Rev Med Pharmacol Sci. 2019 Oct;23(20):8771-8778. doi: 10.26355/eurrev_201910_19271. PMID: 31696463. Liu T, Wang W, Xu YC, Li ZW, Zhou J. Long noncoding RNA NEAT1 functions as an oncogene in human laryngocarcinoma by targeting miR-29a-3p. Eur Rev Med Pharmacol Sci. 2019 Jul;23(14):6234-6241. doi: 10.26355/eurrev_201907_18442. PMID: 31364125. Liu WG, Xu Q. Long non-coding RNA XIST promotes hepatocellular carcinoma progression by sponging miR-200b-3p. Eur Rev Med Pharmacol Sci. 2019 Nov;23(22):9857-9862. doi: 10.26355/eurrev_201911_19549. PMID: 31799653. Weng XD, Yan T, Liu CL. Circular RNA_LARP4 inhibits cell migration and invasion of prostate cancer by targeting FOXO3A. Eur Rev Med Pharmacol Sci. 2020 May;24(10):5303-5309. doi: 10.26355/eurrev_202005_21312. PMID: 32495863. He XY, Pan XM, Jin MM, Yang YL, Yang ZQ, Yan D, Ma JX. Long non-coding RNA AK027294 promotes tumor growth by upregulating PCNA in gastric cancer. Eur Rev Med Pharmacol Sci. 2019 Jul;23(13):5762-5769. doi: 10.26355/eurrev_201907_18314. PMID: 31298327. Wang YH, Huo BL, Li C, Ma G, Cao W. Knockdown of long noncoding RNA SNHG7 inhibits the proliferation and promotes apoptosis of thyroid cancer cells by downregulating BDNF. Eur Rev Med Pharmacol Sci. 2019 Jun;23(11):4815-4821. doi: 10.26355/eurrev_201906_18067. PMID: 31210313. Yang ZT, An F, Hu JD, Zhao WH. Long noncoding RNA AFAP1-AS1 accelerates the proliferation and metastasis of prostate cancer via inhibiting RBM5 expression. Eur Rev Med Pharmacol Sci. 2019 Apr;23(8):3284-3290. doi: 10.26355/eurrev_201904_17690. PMID: 31081081. Ma LY, Xie XW, Ma L, Pang JL, Xiong XM, Zheng HD, Shen XL, Wen ZG, Wang HY. Downregulated long non-coding RNA TRPM2-AS inhibits cisplatin resistance of non-small cell lung cancer cells via activation of p53- p66shc pathway. Eur Rev Med Pharmacol Sci. 2017 Jun;21(11):2626-2634. PMID: 28678322. The following publications have been questioned for showing recurrent structural patterns and visual content (e.g., Kaplan-Meier plots, correlation graphs, etc.) across a large set of articles: Li XF, Aierken AL, Shen L. IPO5 promotes malignant progression of esophageal cancer through activating MMP7. Eur Rev Med Pharmacol Sci. 2020 Apr;24(8):4246-4254. doi: 10.26355/eurrev_202004_21004. PMID: 32373960. Gao WY, Yang G, Wang J, He JM, Wang P. CSN6 promotes malignant progression of oral squamous cell carcinoma by down-regulating TIMP-2. Eur Rev Med Pharmacol Sci. 2020 May;24(10):5419-5428. doi: 10.26355/eurrev_202005_21326. PMID: 32495877. Shi XY, Lin JJ, Ge XJ, Shi Y. LncRNA WTAPP1 promotes proliferation of laryngeal carcinoma cells through regulating microRNA-592. Eur Rev Med Pharmacol Sci. 2020 Sep;24(18):9532-9540. doi: 10.26355/eurrev_202009_23038. PMID: 33015795. Hou YS, Li X. Circ_0005273 induces the aggravation of pancreatic cancer by targeting KLF12. Eur Rev Med Pharmacol Sci. 2020 Nov;24(22):11578-11586. doi: 10.26355/eurrev_202011_23799. PMID: 33275224. Yang Y, Mao FF, Guo L, Guo WX. TRIM56 suppresses the malignant development of hepatocellular carcinoma via targeting RBM24 and inactivating the Wnt signaling. Eur Rev Med Pharmacol Sci. 2021 Jan;25(2):722-730. doi: 10.26355/eurrev_202101_24633. PMID: 33577026. The Publisher apologizes for any inconvenience this may cause.