Category Ranking

98%

Total Visits

921

Avg Visit Duration

2 minutes

Citations

20

Article Abstract

Download full-text PDF

Source
http://dx.doi.org/10.1002/ajpa.70089DOI Listing

Publication Analysis

Top Keywords

interdisciplinary interaction
4
interaction engagement
4
engagement human
4
human remains
4
remains comment
4
comment "they
4
"they people
4
people ethics
4
ethics curation
4
curation human
4

Similar Publications

Integrins from extracellular vesicles as players in tumor microenvironment and metastasis.

Cancer Metastasis Rev

September 2025

Institute for Integrative Biology of the Cell (I2BC), Université Paris-Saclay, CEA, CNRS, Gif-Sur-Yvette, 91198, France.

Integrins constitute a large and diverse family of cell adhesion molecules that play essential roles in regulating tumor cell differentiation, migration, proliferation, and neovascularization. Tumor cell-derived exosomes, a subtype of extracellular vesicles, are enriched with integrins that reflect their cells of origin. These exosomal integrins can promote extracellular matrix remodeling, immune suppression, and vascular remodeling and are closely linked to tumor progression and metastasis, acting as pivotal players in mediating organ-specific metastasis.

View Article and Find Full Text PDF

A clinical and genotype-phenotype analysis of MACF1 variants.

Am J Hum Genet

September 2025

Department of Clinical Genetics, Erasmus MC, University Medical Center Rotterdam, PO Box 2040, Rotterdam 3000 CA, the Netherlands.

Microtubule-actin cross-linking factor 1 (MACF1) is a large protein of the spectraplakin family, which is essential for brain development. MACF1 interacts with microtubules through the growth arrest-specific 2 (Gas2)-related (GAR) domain. Heterozygous MACF1 missense variants affecting the zinc-binding residues in this domain result in a distinctive cortical and brain stem malformation.

View Article and Find Full Text PDF

Nuclear migration plays a fundamental role in development, requiring precise spatiotemporal control of bidirectional movement through dynein and kinesin motors. Here, we uncover a differential isoform-dependent mechanism for developmental regulation of nuclear migration directionality. The nuclear envelope Klarsicht/ANC-1/Syne homology (KASH) protein UNC-83 in Caenorhabditis elegans exists in multiple isoforms that differentially control motor activity to achieve tissue-specific nuclear positioning.

View Article and Find Full Text PDF

Prior researches on global-local processing have focused on hierarchical objects in the visual modality, while the real-world involves multisensory interactions. The present study investigated whether the simultaneous presentation of auditory stimuli influences the recognition of visually hierarchical objects. We added four types of auditory stimuli to the traditional visual hierarchical letters paradigm:no sound (visual-only), a pure tone, a spoken letter that was congruent with the required response (response-congruent), or a spoken letter that was incongruent with it (response-incongruent).

View Article and Find Full Text PDF

Vertically Stacked Boron Nitride/Graphene Heterostructure for Tunable Antiresonant Hollow-Core Fiber.

J Am Chem Soc

September 2025

Center for Nanochemistry, Beijing Science and Engineering Center for Nanocarbons, Beijing National Laboratory for Molecular Sciences, College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, China.

Incorporating atomically thin two-dimensional (2D) materials with optical fibers expands their potential for optoelectronic applications. Recent advancements in chemical vapor deposition have enabled the batch production of these hybrid fibers, paving the way for practical implementation. However, their functionality remains constrained by the integration of a single 2D material, restricting their versatile performance.

View Article and Find Full Text PDF